2008
DOI: 10.1016/j.burns.2007.03.022
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Oxytocin ameliorates skin damage and oxidant gastric injury in rats with thermal trauma

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Cited by 62 publications
(55 citation statements)
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“…[53] Moreover, the protective effect of oxytocin on I/R injury in the liver, kidney, stomach, and urinary bladder have been reported. [54][55][56][57][58] In addition, the anti-apoptotic effect of oxytocin in the heart and ovaries has been revealed. [51,59] However, to our knowledge, the effect of oxytocin on testicular tissues in I/R injured rat model has been reported in only one study.…”
Section: Discussionmentioning
confidence: 99%
“…[53] Moreover, the protective effect of oxytocin on I/R injury in the liver, kidney, stomach, and urinary bladder have been reported. [54][55][56][57][58] In addition, the anti-apoptotic effect of oxytocin in the heart and ovaries has been revealed. [51,59] However, to our knowledge, the effect of oxytocin on testicular tissues in I/R injured rat model has been reported in only one study.…”
Section: Discussionmentioning
confidence: 99%
“…In accordance with its anti-inflammatory effects, analgesic and thermoregulatory effects of OT have also been reported (35). Recently, we have shown its anti-inflammatory effects in colonic inflammation (19), burn injury (18) and renal damage (5,42). We have also shown that OT protects against hepatic injury in sepsis and hepatic ischemia-reperfusion models in the rat (8,17).…”
Section: Anti-inflammatory Effects Of Oxytocin Via the Hpa Axismentioning
confidence: 65%
“…Di er taraftan OT'in iskemik deri fleplerinin ya am süresini uzatt (13), pençede karrageninle indüklenen hiperaljezide inflamasyonu azaltt (14) ve OT'nin bu anti-inflamatuvar etkilerinde büyüme faktörlerinin arac l k etti i gösterilmi tir. Ayr ca, OT'nin s cak su ile olu turulan yan kta sistemik yan t olu turarak doku hasar n ve gastrik mukozal oksidatif hasar n hafifletti i bulundu (15).…”
Section: G Runclassified
“…Bu etki, OT ile indüklenen, büyüme faktörlerine (IGF-1, büyüme hormonu) ya da OT aracılı anti-inflamatuvar mekanizmalara bağlı olabilir (5). Daha önceki çalışmalarımızda OT'nin yanığa bağlı lokal ve uzak organ hasarında etkili olduğunu ve bunu anti-inflamatuvar etkisiyle gerçekleştirdiğini rapor etmiştik (15,26). Ancak, daha önceki çalışmalarımızda OT'nin yanıkla değişen ağrı eşiğine etkisi araştırılmamıştı.…”
Section: Tartişma Ve Sonuçunclassified