This study demonstrates a comparison of energy usage, land footprint and volumetric requirements of municipal wastewater treatment with aerobic granular sludge (AGS) and conventional activated sludge (CAS) at a full‐scale wastewater treatment plant characterized by large fluctuations in nutrient loadings and temperature. The concentration of organic matter in the influent to the AGS was increased by means of hydrolysis and bypassing the pre‐settler. Both treatment lines produced effluent concentrations below 5 mg BOD7 L‐1, 10 mg TN L‐1, and 1 mg TP L‐1, by enhanced biological nitrogen‐ and phosphorus removal. In this case study, the averages of volumetric energy usage over one year were 0.22 ± 0.08 and 0.26 ± 0.07 kWh m‐3 for the AGS and CAS, respectively. A larger difference was observed for the energy usage per reduced P.E., which was on average 0.19 ± 0.08 kWh P.E.‐1 for the AGS and 0.30 ± 0.08 kWh P.E.‐1 for the CAS. However, both processes had the potential for decreased energy usage. Over one year, both processes showed similar fluctuations in energy usage, related to variations in loading, temperature, and DO. The AGS had a lower specific area, 0.3 m2 m‐3 d‐1, compared to 0.6 m2 m‐3 d‐1 of the CAS, and also a lower specific volume, 1.3 m3 m‐3 d‐1 compared to 2.0 m3 m‐3 d‐1. This study confirms that AGS at full‐scale can be compact and still have comparable energy usage as CAS.