Oxygen tension of peripheral tissue

Montgomery, H. E.

doi:10.1016/0002-9343(57)90370-4

Cited by 7 publications

(2 citation statements)

References 20 publications

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“…The renal cortical tissue Po, of 47&18 mm Hg found in normal dogs during respiration of room air correlates well with the Po, of other tissues such as the muscle, skin and heart, recorded under similar conditions (Campbell 1928, Horwitz et al 1950, Montgomery 1957, Bartlett and Tenney 1963. It should be stated that during respiration of air with the animal under Nembutal anesthesia the cortical tissue Po, is slightly lower than the Po, reported for renal venous blood.…”

Section: Discussionsupporting

confidence: 76%

The Influence of Arterial P_O2 on Renal Tissue P_O2

Aperia

1969

Acta Physiologica Scandinavica

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When arterial PO2 is increased to supra‐atmospheric tensions approximating 500 mm Hg in the dog, the PO2 of the renal cortex rises from under 50 mm Hg to the range of 130 mm Hg, in contrast with that of the outer medulla which may even fall; there is little absolute change in the already extremely low PO2 of the inner medulla. These observations are interpreted to support the idea of a homeostatic mechanism operating to regulate medullary blood flow as already suggested by observations of urine PO2 at various arterial O2 tensions. This mechanism helps to maintain the hypoxic state of the medulla appropriate to its relatively anaeroboic metabolism.

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Section: Discussionsupporting

confidence: 76%

The Influence of Arterial P_O2 on Renal Tissue P_O2

Aperia

1969

Acta Physiologica Scandinavica

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“…Continuous records were made of arterial and central venous blood pressures, the electrocardiogram, and tissue oxygen electrode currents, using procedures and systems previously described [6], Because it is not possible to calibrate chronically implanted polarographic electrodes in terms of millimeters of mercury of oxygen partial pressure, we have reported their responses, following the suggestion of Montgomery [5], as a percentage of the difference between the average current measured during the normoxic control period and that measured at the end of the experiment after the animals had received pure nitrogen for 10 min.…”

Section: Methodsmentioning

confidence: 99%

Effects of Shifts in Hemoglobin-Oxygen Affinity During Hypoxia

Rand¹,

Norton²,

Barker³

et al. 1975

Vox Sanguinis

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To investigate the possibility that the influence of hemoglobinoxygen affinity on tissue oxygenation may be reversed in severe hypoxia, 16 anesthetized rabbits with chronically-implanted tissue oxygen electrodes were ventilated with 12% oxygen and subjected to 100 ml exchange transfusions with high, low, or normal affinity rabbit blood. Despite the widely divergent in vivo P(50) values produced, significant differences in tissue oxygen levels were not observed among the three groups following exchange transfusions. During subsequent normoxia, more complete recovery of tissue oxygen was apparent in the low affinity group. This study emphasizes the need for further definition of the influence of hemoglobin-oxygen affinity on the functions of individual organs.

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