Oxygen Saturation Profile in Healthy Term Neonates in the Immediate Post Natal Period

Tiwari, Sucheta

doi:10.4021/ijcp100e

Cited by 6 publications

(6 citation statements)

References 18 publications

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“…It could be because that they are the commonest pediatric age group who are affected by respiratory disorders. Male predominance of 55% among samples is also observed by other studies -Tiwari et al [8] (52%), LeCleir et al [9] (57%) and Ramachandran et al [7] (73%), all of which have not shown any statistical significance.…”

Section: Discussionsupporting

confidence: 69%

Impact of Oxygen Delivery Patterns on Arterial Oxygen Saturation Among Children

Gunjal¹,

Vaidyanathan

Bhosale

2020

Int J Clin Pediatr

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Background: Adequate oxygenation to treat hypoxia by suitable oxygen delivery pattern is the essence of pediatric critical care medicine. Monitoring oxygen saturation (SpO 2) is thus essential in order to decide course of treatment. It is commonly carried out using painless sequential non-invasive pulse oximetry as well by severely painful random arterial blood gas (ABG) analysis. Methods: This study compared both methods to determine the impact of various oxygen delivery patterns upon SpO 2 at bedside for meaningful and continuous evaluation. In a prospective cohort adopted for study, 60 children from acute pediatric wards of an academic tertiary referral hospital were observed. Children were eligible for enrollment using cross sectional approach, if the treating pediatricians ordered an ABG, on pulse oximetry monitoring with oxygen support by any oxygen delivery device using a validated checklist. Results: Among all the samples, 60 % were infants and 55 % were male. Complaints on admission were vomiting (35%), shortness of breath (33%), diarrhea (28%), lethargy (31%) and Kussmaul breathing (30%). SpO 2 was > 90% for 88% of children. Oxy hood box was used to deliver oxygen to 73% of children. SpO 2 had positive correlation with oxygen delivery methods (r = 0.8) and partial pressure of oxygen (PaO 2) by ABG analysis had positive correlation with SpO 2 by pulse oximetry (r = 0.9). Conclusions: Pulse oximetry can be used as a reliable bed side tool to evaluate oxygen delivery patterns and diagnose early respiratory failure in emergency settings where ABG analysis facility is not available.

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Section: Discussionsupporting

confidence: 69%

Impact of Oxygen Delivery Patterns on Arterial Oxygen Saturation Among Children

Gunjal¹,

Vaidyanathan

Bhosale

2020

Int J Clin Pediatr

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“…Several studies from India and other countries have reported SpO 2 and HR values in term newborns after birth, mostly following ECC practice. [36][37][38][39][40] A study in Netherlands newborns documented higher median SpO 2 values for the initial 3 minutes with DCC practice compared with references from Australia/Spain with ECC practice, but the 10th percentile values were higher for the initial 5 minutes. 20,32 The HR values among the Netherland newborns with DCC practices were lower than the Australian/Spanish newborns.…”

Section: Discussionmentioning

confidence: 93%

Is Delaying Cord Clamping until Placenta Delivery Beneficial? Oxygen Saturation and Heart Rate Transition during the Initial 5 Minutes after Delivery in Indian Healthy Newborns

et al. 2019

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Objective This study aimed to compare the preductal oxygen saturation (SpO2) and heart rate (HR) in newborns during the initial 5 minutes after birth with delayed cord clamping (DCC) and early cord clamping (ECC) practices at sea level. Study Design This prospective observational study included newborns born at >34 weeks vaginally (Dharampur, Gujarat) or through caesarean section (CS) (Kolkata, West Bengal). In Dharampur, the newborns received ECC practice (8 weeks) followed by DCC practice (10 weeks). In Kolkata, the newborns received ECC practice only (8 weeks). Results The newborns with DCC (n = 170) had significantly higher SpO2 (3–8%) throughout than those with ECC born either vaginally (n = 178) or through CS (n = 101). The newborns with DCC had slower rise in HR during the first 2 minutes than those with ECC. The 5th and 10th percentile values of SpO2 for newborns with DCC practice were higher than those with ECC practice. Conclusion The trends of SpO2 and HR during the first 5 minutes after birth indicate a relatively smoother cardiopulmonary transition by delaying cord clamping till placental delivery compared with early clamping. The reference ranges can be used for Indian newborns born by uncomplicated vaginal delivery with DCC during the first 5 minutes.

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“…To reduce the toxic effects associated with both to hypoxia and hyperoxia, furthermore in consideration of the data provided by the latest studies, the American Heart Association (AHA) updated guidelines for optimal management of oxygen during resuscitation. AHA stated that room air (21% oxygen) should be used to initiate resuscitation in term and late preterm neonates and that a lower oxygen concentration (21–30%) is recommended to initiate resuscitation of preterm neonates (<35 weeks’ gestation) [ 101 ].…”

Section: Discussionmentioning

confidence: 99%

Oxygen for the Newborn: Friend or Foe?

et al. 2023

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Oxygen supplementation is widely used in neonatal care, however, it can also cause toxic effects if not used properly. Therefore, it appears crucial to find a balance in oxygen administration to avoid damage as a consequence of its insufficient or excessive use. Oxygen toxicity is mainly due to the production of oxygen radicals, molecules normally produced in humans and involved in a myriad of physiological reactions. In the neonatal period, an imbalance between oxidants and antioxidant defenses, the so-called oxidative stress, might occur, causing severe pathological consequences. In this review, we focus on the mechanisms of the production of oxygen radicals and their physiological functions in determining a set of diseases grouped together as “free radical diseases in the neonate”. In addition, we describe the evolution of the oxygenation target recommendations during neonatal resuscitation and post-stabilization phases with the aim to define the best oxygen administration according to the newest evidence.

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Oxygen Saturation Profile in Healthy Term Neonates in the Immediate Post Natal Period

Cited by 6 publications

References 18 publications

Impact of Oxygen Delivery Patterns on Arterial Oxygen Saturation Among Children

Impact of Oxygen Delivery Patterns on Arterial Oxygen Saturation Among Children

Is Delaying Cord Clamping until Placenta Delivery Beneficial? Oxygen Saturation and Heart Rate Transition during the Initial 5 Minutes after Delivery in Indian Healthy Newborns

Oxygen for the Newborn: Friend or Foe?

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