Oxygen: Can you have too much of a good thing?

Frantz, Amanda; Fahy, Brenda G.

doi:10.1016/j.jclinane.2021.110405

Cited by 2 publications

(1 citation statement)

References 8 publications

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“…Although the benefit of improved oxygenation by HFNCO is undoubted, the adverse effects of long-term inhalation of high-concentration or high-flow oxygen remain unknown. High concentrations of oxygen replace the nitrogen in the alveoli, leading to atelectasis [30,31]. Another study demonstrated that HFNCO reduces the occurrence of atelectasis during postoperative long-range deep sedation compared with a mask [32].…”

Section: Discussionmentioning

confidence: 99%

Application of high-flow nasal cannula oxygenation in the induction of general anesthesia by direct providers: A case series

Liu

Meng

Chen

et al. 2022

Preprint

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Background: Pressurized mask-assisted ventilation is commonly used during general anesthesia, which often requires the cooperation of two anesthesiologists and creates a severe shortage of anesthesiologists. High-flow nasal cannula oxygenation (HFNCO) is reportedly effective in perioperative airway management, but its safety and efficacy in the induction of general anesthesia by direct providers have not been confirmed. Methods: Twelve patients were enrolled in our study. Their vital signs were recorded before surgery (T0), and HFNCO was continuously applied after admission. Blood gas analysis results were recorded before pre-oxygenation (T1), during anesthetic induction (T2), and before mechanical ventilation (T3). Results: The mean arterial partial pressure of oxygen (PaO2) was 86.6±26.0, 245.3±90.6, and 170.0±99.4 mmHg at T1, T2, and T3, respectively, and the lowest pulse oxygen saturation (SpO2) was 92% at T3. The mean arterial partial pressure of carbon dioxide (PaCO2) was 39.0±6.2, 40.0±5.7, and 50.2±8.7 mmHg, respectively; the highest was 71.1 mmHg. The mean pH was 7.40±0.02, 7.39±0.05, and 7.35±0.06, respectively. One patient switched to pressurized mask-assisted ventilation because of severe hypoxemia (lowest SpO2, 82%) during apnea oxygenation. Conclusions: HFNCO significantly improves oxygenation levels without severe hypercapnia and can be safely applied to general anesthesia induction by direct providers.

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Section: Discussionmentioning

confidence: 99%

Application of high-flow nasal cannula oxygenation in the induction of general anesthesia by direct providers: A case series

Liu

Meng

Chen

et al. 2022

Preprint

View full text Add to dashboard Cite

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Year 2021 in review - Anaesthesia

Bláha¹

2022

Anest. intenziv. Med.

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Klinika anesteziologie, resuscitace a intenzivní medicíny, 1. lékařská fakulta Univerzity Karlovy a Všeobecná fakultní nemocnice v Praze Zatímco rok 2020 byl významně poznamenán pandemií viru SARS -CoV-2, a to i co se týče publikování, rok 2021 se již vrátil do "publikačního normálu". Skoro do normálu, protože svět, medicína, a ani anestezie už nikdy nebudou, co bývaly. To, co covid-19 změnil, je, že do popředí daleko více vystupuje bezpečnost toho, co děláme. Bezpečnost našich postupů i bezpečnost jednotlivých anestetik, ale nejen. Cílem tohoto textu je ve zkratce shrnout některé klíčové publikace v oblasti anesteziologie a upozornit na práce, které by neměly uniknout pozornosti.

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Oxygen: Can you have too much of a good thing?

Cited by 2 publications

References 8 publications

Application of high-flow nasal cannula oxygenation in the induction of general anesthesia by direct providers: A case series

Application of high-flow nasal cannula oxygenation in the induction of general anesthesia by direct providers: A case series

Year 2021 in review - Anaesthesia

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