Oxidative toxic stress and p53 level in healthy subjects occupationally exposed to outdoor air Pollution – a cross-sectional study in Iran

Respiratory Symptoms and Changes of Oxidative Stress Markers among Motorbike Drivers Chronically Exposed to Air Fine and Ultrafine Particle: The Case of Douala and Dschang, Cameroon

“…The facts appear to be more pronounced among Motorbike Drivers of Douala than those of Dschang. The results of these clinical observations of stress oxidative with exposure against fine or ultrafine particles corroborate with results of Rezaei et al, 2020, who revealed more increased change of blood MDA among healthy occupationally bus drivers, taxi drivers, policeman, and urban service workers exposed to outdoor air pollution in Iran [8]. The same evidence was prior shown by Sorensen et al, 2003 in female students after environmental exposure to air pollutants [22].…”

“…The results on the increase of biological SOD among Motorbikes Drivers of this Study corroborate with those of Davel et al, 2012 on the Rats which showed that exposure to PM2,5 causes enhancing of protein expression of cu/Zn-and Mn-SOD in the pulmonary artery [23]. This evidence differs however those of Rezaei et al, 2020, that showed a decreased change of SOD, among exposed in polluted surroundings in Iran [8]. It is to notice that the magnitude of antioxidative response depends upon the several factors as duration of exposure, ambient fine or ultrafine particle concentration or toxicity, and the susceptibility of the subjects under polluted air [24].…”

“…Indeed, Organism cells possess an antioxidant defence system that consists of the enzymes of superoxide dismutase (SOD), catalase (CAT), glutathione peroxidase (GPx) as well as some nonenzymatic antioxidants such as reduced gluthatione (GSH) and vitamins A, C and E [8,9]. These antioxidants help the organism to tackle deleterious effect of ROS and decrease the cellular damage.…”

Modification of exhaled air nitric oxide in patients with asthma – cortisone monotherapy or dual inhalation therapy?

“…Environmental factors are a major problem in daily life in terms of quality of life and long-term evolution [5]. Mechanical and chemical stress are considered to be factors which induce the growth of free radical production and, as a consequence, tissue oxidative destruction occurs [6]. Tissue oxidative stress assessment has become the target of research on different organs.…”