Oxidative Systems for Modification of Fatty Acids: The Lipoxygenase Pathway

Vick, Brian; Zimmerman, Don C.

doi:10.1016/b978-0-12-675409-4.50009-5

Cited by 116 publications

(154 citation statements)

References 157 publications

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“…2), and this likely applies to potato LOXZ and LOX3. Isoforms of several enzymes of this pathway have been detected in leaf plastids (Douillard and Bergeron, 1981;Vick and Zimmerman, 1987;Song et al, 1993;Feussner et al, 1995;Harms et al, 1995;Blée and Joyard, 1996). Bell et al (1995) showed that the expression of AtLox2 is required for wound-induced JA accumulation in Arabidopsis, and Harms et al (1995) showed that a constitutive increase in JA resulted from the expression of a flax allene oxide synthase in transgenic potato plants (Harms et al, 1995).…”

Section: Discussionmentioning

confidence: 99%

A Gene Encoding a Chloroplast-Targeted Lipoxygenase in Tomato Leaves Is Transiently Induced by Wounding, Systemin, and Methyl Jasmonate

1997

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Section: Discussionmentioning

confidence: 99%

A Gene Encoding a Chloroplast-Targeted Lipoxygenase in Tomato Leaves Is Transiently Induced by Wounding, Systemin, and Methyl Jasmonate

1997

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“…LOX is thought to be involved in the formation of volatile compounds that provide characteristic flavor and odor (Hildebrand, 1989). LOX-catalyzed reactions produce both 9-and 13-hydroperoxide products (Vick and Zimmerman, 1987). The 13-hydroperoxide product is further metabolized into other products, including jasmonic acid, a plant growth regulator, and hexenal, the volatile compound that gives tomato fruit its aroma.…”

Section: Discussionmentioning

confidence: 99%

“…Lipoxygenases are nonheme-iron-containing dioxygenases that catalyze the hydroperoxidation of unsaturated fatty acids containing a cis,cis-1,4-pentadiene structure producing hydroperoxy acids with conjugated dienes (for review, see Vick and Zimmerman, 1987). LOX activity has been found in a wide range of organisms, including plants, animals, fungi, and cyanobacteria (for review, see Siedow, 1991).…”

mentioning

confidence: 99%

Molecular Cloning of a Ripening-Specific Lipoxygenase and Its Expression during Wild-Type and Mutant Tomato Fruit Development

Kausch

Handa

1997

Plant Physiology

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A 94-kD protein that accumulates predominately in tomato (Lycopersicon esculenfum) fruit during ripening was purified, and antibodies specific for the purified protein were used to isolate cDNA clones from a red-ripe fruit cDNA library. A sequence analysis of these cDNAs and cross-reactivity of the 94-kD-specific antibodies to the soybean lipoxygenase (LOX) L-1, L-2, and L-3 proteins and soybean LOX L-l-specific antibodies to the 94-kD protein identified it as a member of the LOX gene family. Maximum levels of the 94-kD LOX mRNA and protein are present in breaker to ripe and red-ripe stages, respectively. Expression of 94-kD LOX in different tissues from mature green and red-ripe tomato fruits was found to be greatest in the radial walls of ripe fruit, but immunocytolocalization using tissue printing suggests that the highest accumulation of its protein occurs in locular jelly. None of 94-kD LOX is expressed in nonripening mutant fruits of any age. Never-ripe mutant fruit accumulate the 94-kD LOX mRNA to levels similar to those obtained in wild-type fruit, but fail to accumulate the 94-kD LOX protein. Collectively, the results show that expression of 94-kD LOX is regulated by the ripening process, and ethylene may play a role in its protein accumulation.

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“…Once the fatty acid hydroperoxide [e.g. 13(S)-hydroperoxide of linolenic acid] is formed because of LOX activity, at least two possible metabolic routes are available in the oxylipin pathway (Vick and Zimmerman, 1987;Hildebrand, 1989). First, HPL will cleave the 18-carbon chain into C,-and C,, moieties and give rise to the C,-aldehydes and C,-alcohols and the C,, product 12-0x0-E-10-dodecenoic acid (traumatin).…”

Section: Discussionmentioning

confidence: 99%

Effect of Volatile Methyl Jasmonate on the Oxylipin Pathway in Tobacco, Cucumber, and Arabidopsis

Avdiushko¹,

Croft²,

Brown³

et al. 1995

Plant Physiol.

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The effect of atmospheric methyl jasmonate on the oxylipin pathway was investigated in leaves of tobacco (Nicotiana tabacum L.), cucumber (Cucumis sativa L.), and Arabidopsis thaliana (L.). Differential sensitivities of test plants to methyl jasmonate were observed. Thus, different concentrations of methyl jasmonate were required for induction of changes in the oxylipin pathway. Arabidopsis was the least and cucumber the most sensitive to methyl jasmonate. Methyl jasmonate induced the accumulation of lipoxygenase protein and a corresponding increase in extractable lipoxygenase activity. Atmospheric methyl jasmonate additionally induced hydroperoxide lyase activity and the enhanced production of severa1 volatile six-carbon products. It is interesting that lipid hydroperoxidase activity, which is a measure of hydroperoxide lyase plus allene oxide synthase plus possibly other lipid hydroperoxidemetabolizing activities, was not changed by methyl jasmonate treatment. Methyl jasmonate selectively altered the activity of certain enzymes of the oxylipin pathway (lipoxygenase and hydroperoxide lyase) and increased the potential of leaves for greatly enhanced six-carbon-volatile production.MJ and JA are thought to be involved in numerous aspects of plant biochemistry. These include wound-induced defense (Farmer and Ryan, 1992;Pena-Cortes et al., 1993) Both JA and MJ are derived from linolenic acid via the oxylipin pathway (Vick and Zimmerman, 1984; Song and Brash, 19911, and there has been speculation that they may fulfill a biochemical and regulatory signaling role in plants '

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Oxidative Systems for Modification of Fatty Acids: The Lipoxygenase Pathway

Cited by 116 publications

References 157 publications

A Gene Encoding a Chloroplast-Targeted Lipoxygenase in Tomato Leaves Is Transiently Induced by Wounding, Systemin, and Methyl Jasmonate

A Gene Encoding a Chloroplast-Targeted Lipoxygenase in Tomato Leaves Is Transiently Induced by Wounding, Systemin, and Methyl Jasmonate

Molecular Cloning of a Ripening-Specific Lipoxygenase and Its Expression during Wild-Type and Mutant Tomato Fruit Development

Effect of Volatile Methyl Jasmonate on the Oxylipin Pathway in Tobacco, Cucumber, and Arabidopsis

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