Oxidative Synthesis of α‐Nitroketones from α‐Substituted Malononitrile and Nitromethane Using Molecular Oxygen without Condensation Reagents

Abstract

We developed an oxidative synthetic method for α‐nitroketones from α‐substituted malononitriles and nitromethane under molecular oxygen. Only base and molecular oxygen are necessary without condensation reagents; this is an environmentally benign synthesis.