2013
DOI: 10.1016/j.exger.2013.06.010
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Oxidative stress in testis of animals during aging with and without reproductive activity

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Cited by 29 publications
(28 citation statements)
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“…Indeed, H 2 O 2 ‐induced oxidative stress in rat Leydig cells has been shown to result in cell apoptosis and testicular dysfunction (Anand et al ., ). Testicular oxidative stress is also involved in ageing and thus causes male infertility (Turner & Lysiak, ; Vazquez‐Memije et al ., ; Salomon et al ., ). Indeed, TBARS and DC levels in testes of aged rats are found significantly increased as compared to those of young ones in this study.…”
Section: Discussionmentioning
confidence: 97%
“…Indeed, H 2 O 2 ‐induced oxidative stress in rat Leydig cells has been shown to result in cell apoptosis and testicular dysfunction (Anand et al ., ). Testicular oxidative stress is also involved in ageing and thus causes male infertility (Turner & Lysiak, ; Vazquez‐Memije et al ., ; Salomon et al ., ). Indeed, TBARS and DC levels in testes of aged rats are found significantly increased as compared to those of young ones in this study.…”
Section: Discussionmentioning
confidence: 97%
“…One of the hypotheses for the effect of the loss of PRDX6 is that there is an ongoing oxidative stress during aging. Indeed, increased levels of reactive oxygen species (ROS) and a decrease in antioxidant enzymes have been reported in aging male rats [40–42] . This aging-associated oxidative stress promotes sperm DNA oxidation and abnormal sperm chromatin in these animals [17,43] .…”
Section: Discussionmentioning
confidence: 99%
“…Although not significant when compared to the younger control, CUR administration increased plasma testosterone levels (Abarikwu, Akiri, Durojaiye, & Alabi, ). Likewise, PTBW was significantly decreased with age (Salomon et al, ). MLT application in the aged rats had the lowest PTBW when compared with the aged control group.…”
Section: Discussionmentioning
confidence: 98%
“…The weight change among the groups was not significant, but the ratio was found to be significant. For this reason, the ratio has been taken into consideration (Salomon et al, ).…”
Section: Methodsmentioning
confidence: 99%