Oxidative Stress and Protein Misfolding in Skin Aging
Tushar Oak,
Riya Patel,
Maushmi S. Kumar
Abstract:Aging is a visible indicator of malfunctioning or toxic proteins that sensitize
other proteins to oxidative damage which is most prominently observed on the skin.
Protein misfolding is caused by the protein following an incorrect folding pathway
which may lead to spontaneous misfolding while oxidative stress refers to the
disruption of the balance between antioxidant defenses and reactive oxygen species
production. Oxidation may alter noncovalent interactions within proteins, peptide chain
fragmentation, and p… Show more
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