2023
DOI: 10.26650/eurjbiol.2023.1348427
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Oxidative Stress and Cancer: Harnessing the Therapeutic Potential of Curcumin and Analogues Against Cancer

Christoffer Lambring,
Liling Chen,
Claire Nelson
et al.

Abstract: Reactive oxygen species (ROS) are a class of bioactive molecules that are the by-products of many cellular functions. These molecules are present in normal cells at homeostatic levels but have been studied extensively in cancer due to their dysregulation resulting in pro- and anti-tumorigenic environments. Completely understanding the paradoxical nature of ROS in cancer is imperative to fully realize its modulation as cancer therapy. Studies into ROS have shown far-reaching effects in cancer, including how ROS… Show more

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“…Reactive oxygen species (ROS) play an important role in the modification of various cell signaling pathways that create an environment conducive to tumor development [ 73 ]. Furthermore, they have an impact on treatment response and the development of drug resistance [ 74 ]. This is due to the ability of free radicals to communicate within and outside of cells, serving as secondary messengers and regulating tumor cell signaling [ 75 ].…”
Section: Resultsmentioning
confidence: 99%
“…Reactive oxygen species (ROS) play an important role in the modification of various cell signaling pathways that create an environment conducive to tumor development [ 73 ]. Furthermore, they have an impact on treatment response and the development of drug resistance [ 74 ]. This is due to the ability of free radicals to communicate within and outside of cells, serving as secondary messengers and regulating tumor cell signaling [ 75 ].…”
Section: Resultsmentioning
confidence: 99%