Oxidative Stress

Finaud, Julien; Lac, G.; Filaire, Edith

doi:10.2165/00007256-200636040-00004

Cited by 604 publications

(320 citation statements)

References 207 publications

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“…In addition, improvements in seminal oxidative status were apparent in HIIT compared to HICT, as HIIT intervention resulted in marked changes in seminal TAC and MDA than those seen in the HICT group. Mechanisms responsible for beneficial effects of chronic exercise on redox balance are traininginduced upregulation of antioxidant enzymes, reduced mitochondrial ROS production and increase in radical scavenging capacity of body tissues and fluids (Finaud et al 2006, Gomes et al 2012. Exerciseinduced upregulation of the antioxidant defense in the HICT and HIIT groups may also explain the observed reductions in seminal markers of oxidative stress in these groups.…”

Section: Discussionmentioning

confidence: 99%

The effects of three different exercise modalities on markers of male reproduction in healthy subjects: a randomized controlled trial

2017

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The aim of this study was to investigate the effects of moderate-intensity continuous training (MICT), high-intensity continuous training (HICT) and high-intensity interval training (HIIT) on markers of male reproduction including seminal markers of oxidative stress and inflammation as well as semen quality and sperm DNA integrity in healthy human subjects. A total of 397 healthy male volunteers were screened and 280 were randomly assigned to one of the MICT (n = 70), HICT (n = 70), HIIT (n = 70) and non-exercise (NON-EX, n = 70) groups. Subjects had inflammatory markers (IL-1β, IL-6, IL-8 and TNF-α), oxidants (ROS, MDA and 8-isoprostane), antioxidants (SOD, catalase and TAC), semen parameters and sperm DNA damage measured at baseline (T 1 ), the end of week 12 (T 2 ), the end of week 24 (T 3 ), and 7 (T 4 ) and 30 days (T 5 ) after training. Chronic MICT, HICT and HIIT attenuated seminal markers of oxidative stress and inflammation with different kinetics for the three types of exercise (P < 0.05), and these changes were correlated with favorable improvements in semen quality parameters and sperm DNA integrity (P < 0.05). MICT was superior to HICT and HIIT in the improvements of markers of male reproductive function (P < 0.05). In conclusion, different exercise modalities favorably affect markers of male reproduction with different kinetics, suggesting intensity-, duration-and type-dependent adaptations to exercise training in healthy human subjects.Reproduction (2017) 153 157-174

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Section: Discussionmentioning

confidence: 99%

The effects of three different exercise modalities on markers of male reproduction in healthy subjects: a randomized controlled trial

2017

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“…However, some activities might not be healthy, due to dehydration, substrate depletion, muscle damage, infl ammation, and the increased production of free radicals. Free radicals, which are particularly produced as a result of physical exercise (Cooper, Vollaard, Choueiri, & Wilson, 2002), are involved in the process of muscle fatigue, many diseases, and aging (Finaud, Lac, & Filaire, 2006). Although there is no defi nitive conclusion on fatigue, it is assumed that two main origins are involved in this process.…”

Section: Introductionmentioning

confidence: 99%

Post-Match Changes in Muscle Damage Markers among U-21 Soccer Players

Trajković¹,

Sporis²,

Vlahović³

et al. 2018

Monten. J. Sports Sci. Med.

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Th is study aimed to investigate the eff ect of offi cial soccer matches on selected markers of muscle damage in U-21 soccer players. A group of 19 trained, healthy male soccer players from the junior category took part in this study. Blood samples were assessed pre-match and immediately aft er a match in response to a competitive (2×45 min) soccer match. Analysis was performed for muscle damage and infl ammatory markers. Signifi cant diff erences between two measures (before and aft er soccer match) exist in Aspartate-aminotransferase (AST), Lactate dehydrogenase (LDH), and Myoglobin. Plasma K + signifi cantly decreased aft er the match (p<0.05), whereas plasma Na + decreased slightly. Th is study showed that most selected markers of muscle damage were infl uenced by a soccer match. However, results remain inconsistent because of the infl uence of the type, duration, and intensity of exercise. Moreover, some markers show great variability among individuals.

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“…1999; Finaud et al. 2006), and measuring the activity of repair systems in vivo is also difficult (Monaghan et al. 2009).…”

Section: Introductionmentioning

confidence: 99%

Plasma markers of oxidative stress are uncorrelated in a wild mammal

Christensen

Selman

Blount

et al. 2015

Ecology and Evolution

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Oxidative stress, which results from an imbalance between the production of potentially damaging reactive oxygen species versus antioxidant defenses and repair mechanisms, has been proposed as an important mediator of life‐history trade‐offs. A plethora of biomarkers associated with oxidative stress exist, but few ecological studies have examined the relationships among different markers in organisms experiencing natural conditions or tested whether those relationships are stable across different environments and demographic groups. It is therefore not clear to what extent studies of different markers can be compared, or whether studies that focus on a single marker can draw general conclusions regarding oxidative stress. We measured widely used markers of oxidative damage (protein carbonyls and malondialdehyde) and antioxidant defense (superoxide dismutase and total antioxidant capacity) from 706 plasma samples collected over a 4‐year period in a wild population of Soay sheep on St Kilda. We quantified the correlation structure among these four markers across the entire sample set and also within separate years, age groups (lambs and adults), and sexes. We found some moderately strong correlations between some pairs of markers when data from all 4 years were pooled. However, these correlations were caused by considerable among‐year variation in mean marker values; correlation coefficients were small and not significantly different from zero after accounting for among‐year variation. Furthermore, within each year, age, and sex subgroup, the pairwise correlation coefficients among the four markers were weak, nonsignificant, and distributed around zero. In addition, principal component analysis confirmed that the four markers represented four independent axes of variation. Our results suggest that plasma markers of oxidative stress may vary dramatically among years, presumably due to environmental conditions, and that this variation can induce population‐level correlations among markers even in the absence of any correlations within contemporaneous subgroups. The absence of any consistent correlations within years or demographic subgroups implies that care must be taken when generalizing from observed relationships with oxidative stress markers, as each marker may reflect different and potentially uncoupled biochemical processes.

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Oxidative Stress

Cited by 604 publications

References 207 publications

The effects of three different exercise modalities on markers of male reproduction in healthy subjects: a randomized controlled trial

The effects of three different exercise modalities on markers of male reproduction in healthy subjects: a randomized controlled trial

Post-Match Changes in Muscle Damage Markers among U-21 Soccer Players

Plasma markers of oxidative stress are uncorrelated in a wild mammal

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