Oxidative methods in the synthesis of vicinal di- and polycarbonyl compounds

The Chemistry of Vicinal Polycarbonyl Compounds

“…There have been several calculations on cyclic polyketones, thioketones, and related systems (Chart 3). Frenking 175 investigated the C 6 S 6 (211) and C 6 O 6 (212) systems in connection with mass spectrometric investigations on C 6 S 6 . Explicitly, he calculated the energy difference of the valence isomers a, b, and c by using ab initio methods.…”

“…A Review Article. A review 212 article appeared in Russian entitled "Oxidative methods in the synthesis of vicinal di-and poly-carbonyl compounds". Some of the methods presented in section II and III of the present review are discussed briefly in this article.…”

A mild and efficient synthesis of aminofurazans

“…The reason for this pronounced DMSO effect is well known Kornblum oxidation of bromomethylketones to the corresponding glyoxals. 27 We next investigated the influence of a co-solvent on the reaction. It appears that activation using DMSO (3 equiv.)…”

Synthesis and X-ray Characterization of Alkali Metal 2-Acyl-1,1,3,3-tetracyanopropenides

“…Currently, a variety of methods for the oxidation of methyl ketones to α-ketoaldehydes have been described. One of the most applied methods involves use of CrO 3 , diphenylselenoxide, or selenium dioxide. , A more safe and accessible reagent is a DMSO–HBr mixture, but this method also has disadvantages, such as a long reaction time (1–24 h) and medium yields (low to 50% on average)…”