Oxidative injury caused by individual and combined exposure of neonicotinoid, organophosphate and herbicide in zebrafish

Shukla, Saurabh; Jhamtani, Reena C.; Dahiya, M. S.; Agarwal, Rakhi

doi:10.1016/j.toxrep.2017.05.002

Cited by 89 publications

(32 citation statements)

References 21 publications

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“…IMI could be cause the hepatotoxicity and nephrotoxicity at a dose much lower than the LD50 in mice [ 14 ]. Moreover, the mixture of neonicotinoid, organophosphate and herbicide cause the oxidative injury in zebrafish [ 15 ]. Inflammation, oxidative stress, DNA damage and apoptosis are induced by several environmental factors, one of which is pesticide intoxication.…”

Section: Introductionmentioning

confidence: 99%

Imidacloprid exposure cause the histopathological changes, activation of TNF-α, iNOS, 8-OHdG biomarkers, and alteration of caspase 3, iNOS, CYP1A, MT1 gene expression levels in common carp (Cyprinus carpio L.)

2018

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Section: Introductionmentioning

confidence: 99%

Imidacloprid exposure cause the histopathological changes, activation of TNF-α, iNOS, 8-OHdG biomarkers, and alteration of caspase 3, iNOS, CYP1A, MT1 gene expression levels in common carp (Cyprinus carpio L.)

2018

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“…In other fish species, sub-chronic exposure to low atrazine increased CAT and SOD activities (56,59), whereas acute exposure generally lowered CAT, GPx, and SOD activities (55,57,58), with exception of neotropical fish, which showed no change (56). Furthermore, in two studies atrazine exposure of Gammarus kischineffensis and shrimp Palaemonetes argentinus resulted in lower CAT but higher SOD activity (61,62).…”

Section: Involvement Of Oxidative Stress In Atrazine Toxicitymentioning

confidence: 91%

Oxidative stress in triazine pesticide toxicity: a review of the main biomarker findings

Semren

Žunec

Pizent

2018

Archives of Industrial Hygiene and Toxicology

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This review article provides a summary of the studies relying on oxidative stress biomarkers (lipid peroxidation and antioxidant enzymes in particular) to investigate the effects of atrazine and terbuthylazine exposure in experimental animals and humans published since 2010. In general, experimental animals showed that atrazine and terbuthylazine exposure mostly affected their antioxidant defences and, to a lesser extent, lipid peroxidation, but the effects varied by the species, sex, age, herbicide concentration, and duration of exposure. Most of the studies involved aquatic organisms as useful and sensitive bio-indicators of environmental pollution and important part of the food chain. In laboratory mice and rats changes in oxidative stress markers were visible only with exposure to high doses of atrazine. Recently, our group reported that low-dose terbuthylazine could also induce oxidative stress in Wistar rats. It is evident that any experimental assessment of pesticide toxic effects should take into account a combination of several oxidative stress and antioxidant defence biomarkers in various tissues and cell compartments. The identified effects in experimental models should then be complemented and validated by epidemiological studies. This is important if we wish to understand the impact of pesticides on human health and to establish safe limits.

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“…In the course of the analysis, two papers overlooked during the development of the original WoE assessment were identified and analyzed. In the end, the papers included in the QWoE update are: (Chang et al 2005;Hecker et al 2005;Svartz et al 2012;Ghodageri and Katti 2013;Olker 2014;Shenoy 2014;Baxter et al 2015;Chen et al 2015;Sai et al 2015Sai et al , 2018Syngenta 2015Syngenta , 2017aSyngenta , 2017bVan Der Kraak et al 2015;Wirbisky and Freeman 2015;dos Santos Mendonc¸a et al 2016;Ehrsam et al 2016;Gustafson et al 2016;Khan et al 2016aKhan et al , 2016bKhan et al , 2016cLiu et al 2016;Richter et al 2016;Russart and Rhen 2016;Tulaby Dezfuly and Mohammadian 2016;Wirbisky et al 2016aWirbisky et al , 2016bWirbisky et al , 2016cD'Angelo and Freeman 2017;Du Gas et al 2017;Hoskins et al 2017;Jones et al 2017;Khalil et al 2017;Kirsten et al 2017;McMahon et al 2017;Persch et al 2017;Scott et al 2017;Shukla et al 2017;Snyder et al 2017;Wang et al 2017;…”

Section: Methodsmentioning

confidence: 99%

“…In a study evaluating oxidative injury in D. rerio exposed to 3000 mg atrazine/L for 24 h, there were no changes in the activity of lipid peroxidase, superoxide dismutase, catalase, glutathione and glutathione peroxidase in liver, kidney, and brain (Shukla et al 2017). A study on the effects of formulated atrazine at 2.5, 5, 10, and 15 mg/L on metabolic parameters in the fish Rhamdia quelen showed a number of changes in total protein, glycogen, total lipids, triacylglycerol and the activity of superoxide dismutase (SOD), catalase (CAT), and concentration of thiobarbituric acid reactive substances (TBARS) in gills, liver, kidney, and muscle (Persch et al 2017).…”

Section: Physiological and Biochemical Effects In Vivomentioning

confidence: 98%

Effects of atrazine on fish, amphibians, and reptiles: update of the analysis based on quantitative weight of evidence

Hanson

Solomon

Kraak

et al. 2019

Critical Reviews in Toxicology

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Quantitative weight of evidence (QWoE) provides a framework and process for evaluating different toxicological studies based on quality and relevance of the results. This framework allows for data from these studies to be combined in separate lines of evidence to address causality, and relevance to environmental risks. In 2014, such a QWoE that examined the body of available company reports and peer reviewed literature regarding the effects of the herbicide atrazine on fish, amphibians, and reptiles was published. Since that time, new studies have been conducted and/or published. One of the advantages of the QWoE framework is that additional information can be added as it becomes available. Thus, these new studies were evaluated in the same manner as previously and the new data incorporated into the existing QWoE. As before, the new updated QWoE was based on the same process of objective scoring of individual studies with respect to the quality of the methods and the relevance of individual responses to the apical endpoints of survival, growth, development, and reproduction. These new data did not identify new responses or indicate any relevant effects of atrazine. The new updated QWoE analysis concluded that atrazine does not adversely affect fish, amphibians, and reptiles, at environmentally relevant concentrations (<100 mg atrazine/L), which is consistent with the previous conclusions. These new studies and data are discussed in this paper and the accompanying supplement information provides detailed and transparent information to support these conclusions.

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Oxidative injury caused by individual and combined exposure of neonicotinoid, organophosphate and herbicide in zebrafish

Abstract: Graphical abstract

Cited by 89 publications

References 21 publications

Imidacloprid exposure cause the histopathological changes, activation of TNF-α, iNOS, 8-OHdG biomarkers, and alteration of caspase 3, iNOS, CYP1A, MT1 gene expression levels in common carp (Cyprinus carpio L.)

Imidacloprid exposure cause the histopathological changes, activation of TNF-α, iNOS, 8-OHdG biomarkers, and alteration of caspase 3, iNOS, CYP1A, MT1 gene expression levels in common carp (Cyprinus carpio L.)

Oxidative stress in triazine pesticide toxicity: a review of the main biomarker findings

Effects of atrazine on fish, amphibians, and reptiles: update of the analysis based on quantitative weight of evidence

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