Oxidation of Ciprofloxacin by Hexacyanoferrate(III) in the Presence of Cu(II) as a Catalyst: A Kinetic Study

Tazwar, Gajala; Jain, Ankita; Mittal, Naveen; Devra, Vijay

doi:10.1002/kin.21097

Cited by 5 publications

(5 citation statements)

References 33 publications

(29 reference statements)

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“…Because of their continued use, the environment impact of such antibacterial agents is of serious concern for public health, so for requires development of the various oxidation process for the transformation and degradation of fluoroquinolones in water. The literature survey reveals that the oxidation of CIP by many oxidants, such as: hexacyanoferrate(III), chloramine-B, Cl2, ClO2, CeSO4, and Fe(VI) [30][31][32][33][34], have been carried out in either alkaline or acidic medium. Studies reveal that the piperazine moiety of CIP is the predominant oxidative site for oxidation [35][36][37][38][39] Literature survey confessed that the kinetics and mechanism of degradation of some antibiotics by colloidal MnO2 in aqueous acidic/alkaline medium have been studied earlier [40][41][42].…”

Section: Introductionmentioning

confidence: 99%

Soluble Colloidal Manganese Dioxide: Formation, Characterization and Application in Oxidative Kinetic Study of Ciprofloxacin

Tazwar¹,

Devra²

2019

Bull. Chem. React. Eng. Catal.

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Soluble colloidal manganese dioxide was formed by reduction of potassium permanganate with sodium thiosulphate in neutral aqueous medium at 25 ºC. The obtained nano-sized colloidal manganese dioxide was found to be dark reddish-brown in color and stable for several months. The formation of manganese dioxide was confirmed by UV-visible spectrophotometer and determination of oxidation state of Mn species in manganese dioxide. The effect of different concentration of sodium thiosulphate on the formation of manganese dioxide was also studied. The nano-sized colloid manganese dioxide was characterized by transmission electron microscopy and Fourier transform infrared spectrophotometer. The formed soluble colloidal manganese dioxide was used as an oxidant in oxidation of ciprofloxacin in perchloric acid medium at 35 ºC. The reaction was first-order concerning to concentration of manganese dioxide and hydrogen ion but fractional order with ciprofloxacin. The results suggest formation of complex between ciprofloxacin and manganese dioxide. The oxidation products were also identified based on stoichiometric and characterization results. Copyright © 2020 BCREC Group. All rights reserved

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Section: Introductionmentioning

confidence: 99%

Soluble Colloidal Manganese Dioxide: Formation, Characterization and Application in Oxidative Kinetic Study of Ciprofloxacin

Tazwar¹,

Devra²

2019

Bull. Chem. React. Eng. Catal.

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“…This intermediate complex reacts with the oxidant in rate determining step, since order with respect to HCF(III) and Cu(II) is one each, the order with respect to OFL is fractional. Furthermore, rate also increases with increasing concentration of hydroxyl ion [27]. The reaction proceed more rapidly with the presence of copper(II) ion as a catalyst.…”

Section: Mechanism For Cu(ii) Catalyzed Reactionmentioning

confidence: 92%

Kinetic study of uncatalyzed and Cu(II) catalyzed oxidation of ofloxacin in aqueous alkaline medium and their mechanistic aspects

Tazwar¹,

Devra²

2019

SN Appl. Sci.

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The presence and accumulation of antibacterial drugs in environment, may pose threats to the ecosystem and human health. Hence, oxidation process is of significant to minimize possibility of health risk. The present study aimed to uncatalyzed and Cu(II) catalyzed oxidative degradation of antibacterial drug ofloxacin by hexacyanoferrate(III) in aqueous alkaline medium at 40 °C temperature. The stoichiometry of the reaction indicates that the oxidation of 1 mol of ofloxacin requires 2 mol of hexacyanoferrate(III). The uncatalyzed reaction exhibited first order kinetics with respect to [hexacyanoferrate(III)] and [ofloxacin] and less than unit order with respect to [OH − ]. The catalyzed reaction gives first order kinetics with respect to [hexacyanoferrate(III)] and [OH − ] and less than unit order with respect to [ofloxacin]. The products were also identified on the basis of stoichiometric results and confirm by the characterization results of liquid chromatography mass spectroscopy and Fourier transform infrared analysis. The major product of the reaction obtained by the decarboxylation of the quinolones moiety and hence it may retain the antibacterial activity. Uncatalyzed reaction simultaneously occurs with the Cu(II) catalyzed reaction and the following rate law confirms to all experimental data observed in the reaction: k �� = k un + K 1 K 3 k[Cu(II)][OH − ][OFL] K 2 +K 3 [OFL] , where k ′′ = (k un + k c) is the total observed first order rate constant, k un = Pseudo first order rate constant for uncatalyzed reaction, K c = Pseudo first order rate constant for catalyzed reaction. A reaction mechanism accounting for all these experimental results has been suggested.

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“…If phthalimide did not show any effect and acid followed positive fractional order then NBP or protonated NBP will be reactive species for the oxidation process (Eqs. 3,4).…”

Section: Properties Of Nbpmentioning

confidence: 99%

“…It includes remediation of pollutants or combustion process. Nowadays, study of oxidation of organic compounds present in environment is of immense importance and there are several oxidants reported for degradation processes [1][2][3]. With the passage of time, detailed study of the kinetics and mechanism of redox reaction has draw much attention, and mechanisms of various oxidation reactions have been neatly explained [4,5].…”

Section: Introductionmentioning

confidence: 99%

Oxidative behavior of N-bromophthalimide for organic compounds: a review

Jain¹,

Negi

Singh³

2018

SN Appl. Sci.

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Organic compounds receive from industries as effluents are highly toxic and hazardous for the environment. Conventional oxidation process for the oxidation of organic compounds through use of N-bromophthalimide (NBP) is one of the significant process for conversion of organic compounds into environmental friendly or less harmful substances. The main scenario of this review is oxidation and kinetics of different organic compounds by NBP with different experimental methods-iodometric and potentiometric along with uncatalyzed, and catalyzed system. In addition to this we also summarize synthesis, properties and reactive species of NBP. Oxidation products obtained by oxidation of various organic compounds by NBP were acetic acid, aldehyde, carbon dioxide, ammonia, cyanide, aldonic acid etc. Present review, first time offers all aspects of NBP as an oxidizing agent for oxidation of organic compounds.

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Oxidation of Ciprofloxacin by Hexacyanoferrate(III) in the Presence of Cu(II) as a Catalyst: A Kinetic Study

Cited by 5 publications

References 33 publications

Soluble Colloidal Manganese Dioxide: Formation, Characterization and Application in Oxidative Kinetic Study of Ciprofloxacin

Soluble Colloidal Manganese Dioxide: Formation, Characterization and Application in Oxidative Kinetic Study of Ciprofloxacin

Kinetic study of uncatalyzed and Cu(II) catalyzed oxidation of ofloxacin in aqueous alkaline medium and their mechanistic aspects

Oxidative behavior of N-bromophthalimide for organic compounds: a review

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