Oxidation and chlorination reactions of perfluoroketene-N,S-acetals

Synthesis of Fluorinated Amide Derivatives via a Radical N-Perfluoroalkylation–Defluorination Pathway

“…We envisioned that thioamide derivatives could be obtained under similar conditions. Such a procedure could serve as an alternative method for the synthesis of fluorinated thioamides . Unlike the oxydefluorination with NaOAc, the thioacetate-promoted reaction led to the formation of thioamides 5 , involving a concomitant cleavage of the N–O bond.…”