Ovulation Induction With Low Doses of Clomiphene Citrate

Dodge, Steven T.; Strickler, Ronald C.; Keller, David W.

doi:10.1097/00006250-198603001-00019

Cited by 26 publications

(6 citation statements)

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“…Follow-up were done when next menstruation was missed with urine pregnancy test (UPT) and sonography as per standard international infertility management protocol. [3][4][5][6] Primary outcomes measured were-ET on day of IUI in both groups, number of 'no' pregnancy, number of 'biochemical' pregnancies (UPT positive without gestation sac on sonography) and number of sonological/ clinical pregnancies diagnosed by appearance of gestational sac.…”

Section: Methodsmentioning

confidence: 99%

Relation of endometrial thickness and pregnancy rates in intrauterine insemination following ovulation induction

Biswas¹,

Bandhu

Singh³

et al. 2016

Int J Reprod Contracept Obstet Gynecol

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Section: Methodsmentioning

confidence: 99%

Relation of endometrial thickness and pregnancy rates in intrauterine insemination following ovulation induction

Biswas¹,

Bandhu

Singh³

et al. 2016

Int J Reprod Contracept Obstet Gynecol

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“…Earthy colored and Farquhar, [25] detailed that helpless forecast for origination if the endometrial thickness on ultrasound filtering doesn't arrive at 8mm at ovulation and whenever noted in the primary pattern of treatment with CC, it will in all likelihood be seen in rehashed cycles in a similar lady. There is little point in enduring after even one cycle, and a stage up to different types of ovulation enlistment is suggested [26].…”

Section: Comparison Between Induction Of Ovulation Withmentioning

confidence: 99%

Comparison between Induction of Ovulation with Clomiphene Citrate with or without Withdrawal Bleeding in Patients with Polycystic Ovary Syndrome

Elbery

Asar

Bayomy

et al. 2020

Benha Journal of Applied Sciences

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Polycystic ovary condition (PCOS) is a typical heritable and heterogeneous issue described by ovulatory brokenness with hyperandrogenic status, notwithstanding the polycystic morphology of the ovaries. Treatment of anovulation begins with weight decrease in fat ladies, through to careful control of the ovaries. A few medicines been utilized for acceptance of ovulation. This investigation expected to assess the impact of clomiphene citrate in enlistment of ovulation in patients with polycystic ovarian syndrome(PCOs) without prompting withdrawal seeping in examination with the conventional convention of clomiphene citrate. Techniques: complete of 60 barren ladies matured 20 -40 years of age with the conclusion of PCOS , who introduced to Benha University Hospital at the barrenness outpatient facility , were enrolled for the investigation , all patients were arbitrarily isolated into two gathering :Group 1 (study gathering ): Group II (Control gathering ): Transvagina l ultrasound folliculometry was done 5 -7 days after finish of CC treatment . Results: This examination had indicated that the all out number of follicles, mean follicular width and endometrial thickness after incitement was altogether more when beginning CC in (luteal stage) than (follicular phase).Conclusion:Early organization of CC in late luteal stage (before withdrawal shedding) in patients with PCOS may prompt more follicular development, ovulatory patients and endometrial thickness which may ponder higher pregnancy rate than organization of CC in early follicular stage (from second day to fifth day of cycle).

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“…The side-effects are dose-dependent. Doses lower than 50 mg/day may be considered for women (continued on next page) who have experienced ovarian hyper response after a dose of 50 mg/day for 5 days (Dodge et al, 1986). The ovarian response is correlated to the body weight (Dickey et al, 2002;Lobo et al, 1982).…”

Section: Clomiphene Citrate Dosingmentioning

confidence: 99%

Mono-ovulation in women with polycystic ovary syndrome: a clinical review on ovulation induction

Petersen

Pedersen

et al. 2016

Reproductive BioMedicine Online

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Polycystic ovary syndrome (PCOS) affects 5-10% of women of reproductive age and is the most common cause of anovulatory infertility. The treatment approaches to ovulation induction vary in efficacy, treatment duration and patient friendliness. The aim was to determine the most efficient, evidence-based method to achieve mono-ovulation in women diagnosed with PCOS. Publications in English providing information on treatment, efficacy and complication rates were included until September 2015. Systematic reviews, meta-analyses and randomized controlled trials were favoured over cohort and retrospective studies. Clomiphene citrate is recommended as primary treatment for PCOS-related infertility. It induces ovulation in three out of four patients, the risk of multiple pregnancies is modest and the treatment is simple and inexpensive. Gonadotrophins are highly efficient in a low-dose step-up regimen. Ovulation rates are improved by lifestyle interventions in overweight women. Metformin may improve the menstrual cycle within 1-3 months, but does not improve the live birth rate. Letrozole is effective for ovulation induction, but is an off-label drug in many countries. Ovulation induction in women with PCOS should be individualized with regard to weight, treatment efficacy and patient preferences with the aim of achieving mono-ovulation and subsequently the birth of a singleton baby.

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Ovulation Induction With Low Doses of Clomiphene Citrate

Cited by 26 publications

References 0 publications

Relation of endometrial thickness and pregnancy rates in intrauterine insemination following ovulation induction

Relation of endometrial thickness and pregnancy rates in intrauterine insemination following ovulation induction

Comparison between Induction of Ovulation with Clomiphene Citrate with or without Withdrawal Bleeding in Patients with Polycystic Ovary Syndrome

Mono-ovulation in women with polycystic ovary syndrome: a clinical review on ovulation induction

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