Ovicidal and Larvicidal Activities of Ethanolic Leaf Extracts of Three Botanicals Against the Malaria Vector - Anopheles Gambiae

Egunjobi, Funmilayo Bukola; Okoye, Ikem Chris

doi:10.21467/ias.9.1.111-121

Cited by 6 publications

(3 citation statements)

References 43 publications

(34 reference statements)

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“…purpureum and T . procumbens with LC 50 values of 17.380ppm and 39.198ppm respectively [ 44 ]. The current study also investigated the pupicidal activity against the pupae of the three mosquito species selected for the study.…”

Section: Resultsmentioning

confidence: 99%

Ovicidal, larvicidal and pupicidal efficacy of silver nanoparticles synthesized by Bacillus marisflavi against the chosen mosquito species

J.¹,

Balasubramanian²

2021

PLoS ONE

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Microbial synthesis of silver nanoparticles is more advantageous and is eco-friendly to combat the various vectors that cause diseases in humans. Hence, in the present study a Bacillus strain is isolated from marine habitat and is evaluated for its ability to synthesize silver nanoparticles (AgNPs) and its efficacy evaluated against the immature stages of selected mosquito species. The effective candidate was confirmed to be Bacillus marisflavi after 16S rRNA sequencing. The synthesis of AgNPs was confirmed by UV-Vis spectrophotometer. Atomic Force Microscopic (AFM) analysis showed spherical nanoparticles. Size analysis using Scanning Electron Microscope (SEM) showed particles of nano size averaging 78.77 nm. The diameter of the particles analyzed by Dynamic Light Scattering (DLS) showed 101.6 nm with a poly-dispersive index of 0.3. Finally the elemental nature of the nanoparticles was identified by Fourier-transform infrared spectroscopy (FTIR). LC50 and LC90 values for the ovicidal, larvicidal and pupicidal efficacy of the AgNPs against the egg, larvae and pupae of Aedes aegypti, Culex quinquefasciatus and Anopheles stephensi respectively were evaluated. The present study revealed that the nanoparticles have an excellent toxic effect against the disease transmitting vector mosquitoes. Hence, the rapid synthesis of AgNPs would be an appropriate eco-friendly tool for biocontrol of vector mosquitoes.

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Section: Resultsmentioning

confidence: 99%

Ovicidal, larvicidal and pupicidal efficacy of silver nanoparticles synthesized by Bacillus marisflavi against the chosen mosquito species

J.¹,

Balasubramanian²

2021

PLoS ONE

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“…Inoculum was prepared from the parasitized (with P. berghei) blood collected from the donor mice. Blood was serially diluted with normal saline solution to make a suspension so that 0.2 mL contained approximately1x10 7 infected RBC (red blood cells). 11…”

Section: Inoculation Of Parasitesmentioning

confidence: 99%

“…5,6 The phytoconstituents of the plant include flavonoids, tannins, alkaloids and saponins. 7 Herein, the antimalarial potentials as well as the phytoconstituents of P. purpureum leaf extract and fractions are reported. *Corresponding author.…”

Section: Introductionmentioning

confidence: 99%

In vivo Antimalarial and GC-MS Studies of Pennisetum purpureum Leaf Extract and Fractions

2022

TJNPR

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Pennisetum purpureum (elephant grass) is a plant used in ethnomedicine for malaria treatment. The present study was aimed at investigating the antimalarial potential of P. purpureum leaf and to identify its phytoconstituents. The leaves were extracted with methanol to afford the crude extract which was successively partitioned between water and n-hexane, dichloromethane, ethyl acetate and n-butanol to afford the fractions. The acute toxicity study was done in mice. Mice were infected with Plasmodium berghei and then treated (p.o.) with the crude extract in the curative and suppressive antimalarial models at three doses (100, 200 and 400 mg/kg). Another set of infected mice was also treated orally with 200 mg/kg of each of the fractions in a suppressive model. The reference drug used for both models was artemeter/lumefantrine (7 mg/kg A/L). The most active fraction, the n-hexane fraction, was subjected to further analysis by GC-MS. The crude extract lethal dose (LD50) was established as 1702.94 mg/kg. The crude extract showed a plasmodial inhibitory activity in the range of 46.20 to 59.90% in the curative model. Both the extract and fractions displayed chemo-suppressive activity (p<0.05) in the range of 66.90 to 96.50%. The A/L produced (p<0.05) 69.00% inhibitory and 95.20% chemosuppressive activities. The results of GC-MS showed the presence of 21 compounds. It was concluded that the extract and fractions of P. purpureum displayed strong antimalarial activity in both models which provides justification for the use of the plant in traditional medicine for malarial treatment.

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The Influence of Portulaca Oleracea L. Leaves Extracts on the Histoarchitecture of Culex Quinquefasciatus and Anopheles Stephensi Larvae

Sudharsan¹,

Siva²,

Prabhu³

et al. 2022

Clinical Complementary Medicine and Pharmacology

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Ovicidal and Larvicidal Activities of Ethanolic Leaf Extracts of Three Botanicals Against the Malaria Vector - Anopheles Gambiae

Cited by 6 publications

References 43 publications

Ovicidal, larvicidal and pupicidal efficacy of silver nanoparticles synthesized by Bacillus marisflavi against the chosen mosquito species

Ovicidal, larvicidal and pupicidal efficacy of silver nanoparticles synthesized by Bacillus marisflavi against the chosen mosquito species

In vivo Antimalarial and GC-MS Studies of Pennisetum purpureum Leaf Extract and Fractions

The Influence of Portulaca Oleracea L. Leaves Extracts on the Histoarchitecture of Culex Quinquefasciatus and Anopheles Stephensi Larvae

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