“…In another overview on the polyphenol avenanthramide, a group of polyphenolic compounds found abundantly in oat (Avena sativa Linn. ), as regulators of PI3K signaling in the management of neurodegenerative diseases, Wankhede and colleagues [15] report that these compounds have been shown to modulate PI3K/AKT signaling. Since the dysregulation of PI3K signaling has been implicated in the pathogenesis of various neurodegenerative diseases such as Alzheimer's and Parkinson's, the recovery of regular activity might lead to increased neuronal survival, reduced oxidative stress, and improved cognitive function.…”