2012
DOI: 10.1016/j.jecm.2012.02.001
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Overview of the Diagnosis and Treatment of Stuttering

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Cited by 33 publications
(25 citation statements)
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“…Another possible explanation is the indirect effect of balcofen on the dopamine system. It has been shown that stuttering is related to higher levels of dopamine activity25 and that dopamine antagonists like haloperidol or risperidone can improve stuttering 26. Baclofen will lead to a stimulation of GABA-B receptors , resulting in the inhibition of dopamine release in the surrounding dopaminergic neurons, which in turn may cause an amelioration of stuttering.…”
Section: Discussionmentioning
confidence: 99%
“…Another possible explanation is the indirect effect of balcofen on the dopamine system. It has been shown that stuttering is related to higher levels of dopamine activity25 and that dopamine antagonists like haloperidol or risperidone can improve stuttering 26. Baclofen will lead to a stimulation of GABA-B receptors , resulting in the inhibition of dopamine release in the surrounding dopaminergic neurons, which in turn may cause an amelioration of stuttering.…”
Section: Discussionmentioning
confidence: 99%
“…Stutterers are likely to exhibit a hypometabolism of the striatum and increased dopamine activity 1,24. Overactivity in the area of the basal ganglia in PDS has been reported in several studies, suggesting that the dopaminergic system plays an important role in the development of stuttering 25,26.…”
Section: Discussionmentioning
confidence: 99%
“…Coexisting symptoms may include facial grimacing and tremors of the muscles involved in speech 1. Stuttering affects approximately 5% of children and 1% of the adult population 1. Most stuttering undergoes spontaneous recovery 1.…”
Section: Introductionmentioning
confidence: 99%
“…“The smaller polarity of affected males versus females near the time of onset as compared with the polarity at more advanced ages suggests that recovery from stuttering is considerably more frequent in girls than in boys” [1]. Recovery from developmental stuttering without any intervention occurs in about 75% of persons [2]. Acquired stuttering which can occur at any age is resulted from secondary causes such as drugs, head trauma, stroke, and brain tumors [2-4].…”
Section: Introductionmentioning
confidence: 99%
“…Recovery from developmental stuttering without any intervention occurs in about 75% of persons [2]. Acquired stuttering which can occur at any age is resulted from secondary causes such as drugs, head trauma, stroke, and brain tumors [2-4]. Most published reports of drug induced stuttering have noted psychotropics such as bupropion [5], clozapine [6,7], topiramate [8], lithium [4], tricyclic antidepressants [5,9], phenothiazines [5,9,10], selective serotonin reuptake inhibitors (sertraline and fluoxetine) [5,9], risperidone [11], olanzapine [7], stimulants [9,10,12] as responsible agents.…”
Section: Introductionmentioning
confidence: 99%