Overview of Systematic Reviews of Non–Vitamin K Oral Anticoagulants in Atrial Fibrillation

Doundoulakis, Ioannis; Antza, Christina; Apostolidou-Kiouti, Fani; Akrivos, Evangelos; Karvounis, Haralambos; Kotsis, Vasilios; Haidich, Anna‐Bettina; Giannakoulas, George

doi:10.1161/circoutcomes.118.004769

Cited by 23 publications

(18 citation statements)

References 8 publications

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“…SRs. [48][49][50][51][52] The production of SRs has markedly increased across several disciplines. Recent studies concluded that the number of RCTs published has been extremely small compared to the mass production of SRs.…”

Section: Current Problems With Srsmentioning

confidence: 99%

“…Recent studies concluded that the number of RCTs published has been extremely small compared to the mass production of SRs. 48,49 Conversely, the number of SRs has increased compared to the number of RCTs, and SRs with overlapping themes are increasing worldwide. Redundant SRs add to the ongoing waste of research resources, time, and effort across disciplines.…”

Section: Current Problems With Srsmentioning

confidence: 99%

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<p>Overview of Systematic Reviews with Meta-Analysis Based on Randomized Controlled Trials of Balneotherapy and Spa Therapy from 2000 to 2019</p>

Kamioka

Nobuoka

Iiyama

2020

IJGM

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Background: The objectives of this review were to summarize systematic reviews with meta-analysis of balneotherapy (BT) and spa therapy (ST) based on randomized controlled trials, and to provide a perspective for future research. Methods: Eligible studies were systematic reviews based on randomized controlled trials with meta-analysis that included at least one group treated with BT or ST. We searched the following databases for articles published in English from the year 2000 to 20 November 2019: Cochrane Database Systematic Review, MEDLINE, CINAHL, Web of Science, and Ichushi-Web. Results: Eighteen studies met all inclusion criteria. Based on the International Classification of Diseases (ICD)-11, among these 18 studies, 8 (44%) were about "#15 Diseases of the musculoskeletal system or connective tissue", 5 (28%) were about "#21 Symptoms, signs or clinical findings, not elsewhere classified", 4 (22%) were about "#11 Diseases of the circulatory system", and 1 study (6%) was about "#8 Diseases of the nervous system". Both BT and ST provided significant pain relief and improved quality of life in chronic diseases of the musculoskeletal system and connective tissues. Additionally, BT and ST with exercise under water improved physical fitness and function in patients across diseases. Conclusion: Researchers need to conduct studies on the treatment of many kinds of potential diseases using the keywords of pain relief and QoL. In addition, depending on patients' symptoms, physical fitness, and disabilities, performing exercise under water may improve treatment effects on physical function and fitness.

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Section: Current Problems With Srsmentioning

confidence: 99%

Section: Current Problems With Srsmentioning

confidence: 99%

<p>Overview of Systematic Reviews with Meta-Analysis Based on Randomized Controlled Trials of Balneotherapy and Spa Therapy from 2000 to 2019</p>

Kamioka

Nobuoka

Iiyama

2020

IJGM

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“…The compelling scientific case for replicating systematic reviews is complicated by research waste concerns (eg, multiple reviews of the same question outnumbering the original studies) 56. The term “duplication” has been used to refer to needless, frequently unwitting or unacknowledged repetition without a clearly defined purpose for the repetition 78.…”

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confidence: 99%

When to replicate systematic reviews of interventions: consensus checklist

Tugwell

Welch

Karunananthan

et al. 2020

BMJ

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“…The number of published systematic reviews being produced yearly is also expanding [2,3], and duplication of reviews on similar topics is common. For example, Doundoulakis et al [4] found 57 meta-analyses on direct oral anticoagulants for stroke prevention in atrial brillation. Their inclusion criteria were meta-analyses with comprehensive search strategies and risk of bias assessments.…”

Section: Introductionmentioning

confidence: 99%

Managing Overlap of Primary Studies Results Across Systematic Reviews: Practical Considerations for Authors of Overviews of Reviews

Lunny

Pieper

Thabet

et al. 2021

Preprint

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Background: In overviews, inclusion of the same primary study in multiple systematic review gives undue weight to this study. Using a study result multiple times in the same analysis overstates its sample size and number of events, falsely leading to greater precision in the analysis. This paper aims to: (a) describe types of overlapping data that arise from the same primary studies reported across multiple reviews, (b) describe methods to identify and explain overlap of primary study data, and (c) present six case studies illustrating different approaches to manage overlap. Methods: We first updated the search in PubMed for methods from the MOoR framework relating to overlap of primary studies. One author screened the studies titles and abstracts, and any full-text articles retrieved, extracted methods data relating to overlap of primary studies and mapped it to the overlap methods from the MOoR framework. We also describe six case studies as examples of overviews that use specific methods across the steps in the conduct of an overview. For each case study, we discuss potential implications in terms of methodological limitations, efficiency, usability, and resource use.Results: Eight studies were mapped to the methods identified by the MOoR framework to address overlap. Several overlap methods mapped across four steps in the conduct of an overview – the eligibility criteria step, the data extraction step, the assessment of risk of bias step, and the synthesis step. Our overview case studies used multiple methods to reduce overlap at different steps in the conduct of an overview.Conclusions: Our study underlines that there is currently no standard methodological approach to deal with overlap in primary studies across reviews. The level of complexity when dealing with overlap can vary depending on the yield, trends and patterns of the included literature and the scope of the overview question. Choosing a method might be dependent on the number of included reviews and their primary studies. Gaps in in evaluation of methods to address overlap were found and further investigation in this area is needed.

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Overview of Systematic Reviews of Non–Vitamin K Oral Anticoagulants in Atrial Fibrillation

Cited by 23 publications

References 8 publications

<p>Overview of Systematic Reviews with Meta-Analysis Based on Randomized Controlled Trials of Balneotherapy and Spa Therapy from 2000 to 2019</p>

<p>Overview of Systematic Reviews with Meta-Analysis Based on Randomized Controlled Trials of Balneotherapy and Spa Therapy from 2000 to 2019</p>

When to replicate systematic reviews of interventions: consensus checklist

Managing Overlap of Primary Studies Results Across Systematic Reviews: Practical Considerations for Authors of Overviews of Reviews

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