Overview of magnesium-ceramic composites: mechanical, corrosion and biological properties

Khorashadizade, Faeze; Abazari, Somayeh; Rajabi, Majid; Bakhsheshi‐Rad, Hamid Reza; Ismail, Ahmad Fauzi; Sharif, Safian; Ramakrishna, Seeram; Berto, Filippo

doi:10.1016/j.jmrt.2021.10.141

Cited by 84 publications

(21 citation statements)

References 200 publications

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“…Therefore, MP-WH also contains trace elements including Mg [ 29 ]. Khorashadizade et al [ 30 ] reported that HAp ceramics containing Mg had a higher mechanical strength than that of HAP ceramics that did not contain Mg. This is owing to the crystal structure according to the atomic arrangement of the ceramic powder, which differs based on the presence or absence of Mg [ 30 ].…”

Section: Discussionmentioning

confidence: 99%

“…Khorashadizade et al [ 30 ] reported that HAp ceramics containing Mg had a higher mechanical strength than that of HAP ceramics that did not contain Mg. This is owing to the crystal structure according to the atomic arrangement of the ceramic powder, which differs based on the presence or absence of Mg [ 30 ]. Therefore, the increased compressive strength of the MP-WH scaffold may be attributed to the crystal structure of the WH material.…”

Section: Discussionmentioning

confidence: 99%

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Marine Plankton-Derived Whitlockite Powder-Based 3D-Printed Porous Scaffold for Bone Tissue Engineering

et al. 2022

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Powder-based 3D printing is an excellent technique for the fabrication of complex structural shapes. The outstanding bone remodeling capacity of calcium phosphate bioceramics is a desirable characteristic for such fabrication. Whitlockite (WH) is a calcium phosphate-based ceramic that contains Mg ions and possesses good mechanical properties, rapid resorbability, and promotes osteogenesis. The aim of this study was to fabricate 3D-printed scaffolds using marine plankton-derived WH (MP-WH) powder. The surface morphology and composition of the fabricated scaffolds were characterized by scanning electron microscopy and X-ray diffraction. The biocompatibility and osteogenic effects were evaluated using human mesenchymal stem cells. We successfully obtained a 3D porous scaffold using MP-WH. The MP-WH 3D scaffold showed improved compressive strength compared to the tricalcium phosphate (TCP) 3D scaffold. The in vitro results showed that compared with TCP 3D scaffolds, MP-WH 3D scaffolds were biocompatible and enhanced cell proliferation and adhesion. In addition, alkaline phosphatase activity and real-time polymerase chain reaction assays demonstrated that osteoblast differentiation was improved on the MP-WH scaffold. These results suggest that marine plankton-derived WH is useful for fabricating 3D-printed scaffolds for bone tissue engineering applications.

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Section: Discussionmentioning

confidence: 99%

Section: Discussionmentioning

confidence: 99%

Marine Plankton-Derived Whitlockite Powder-Based 3D-Printed Porous Scaffold for Bone Tissue Engineering

et al. 2022

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“…Ti as a matrix material provides strength to the implant, whereas Mg reduces the elasticity, thus minimizing the stress shielding effect during loading, and selectively dilutes the Mg into the surface and volume of the implant over time, resulting in the formation of gradient porosity. [61,62] Dilution of the Mg phase will improve the osseointegration process due to increased porosity. The strength and ε values of the alloys gradually decrease with increasing Mg content.…”

Section: Mechanical Properties Strengtheningmentioning

confidence: 99%

Strengthening Mechanisms of Ti–Mg Composite for Biomaterials: A Review

Xue,

Luo,

Zhang

et al. 2023

Adv Eng Mater

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Titanium (Ti) has been widely used in biomedical implants due to its excellent mechanical properties and biocompatibility. However, the “stress shielding” effect greatly limits the application of titanium alloys in medical devices. Studies have shown that the incorporation of bioactive elements into the titanium alloy matrix is an effective way to impart specific biological functions to the material through the sustained release of biofunctional elements. Magnesium (Mg) and its alloys have good bioactivity and are potential candidates for biodegradable metal implants. Ti–Mg composites are of increasing interest for biomedical applications. However, the incompatibility between Ti and Mg, such as immiscibility and large melting point difference, has been a great obstacle in preparing Ti–Mg composites. In addition, the biocompatibility of Ti–Mg metal matrix composites in vivo still needs to be further investigated. Herein, the recent research progress of Ti–Mg composites for biomedical implants is reviewed, focusing on their preparation methods and properties. The preparation methods such as powder metallurgy technology and 3D printing are introduced in detail. In addition, the mechanical and corrosion resistance as well as biocompatibility of Ti–Mg composites are discussed. Based on this, the problems and development prospects of Ti–Mg metal matrix composites are presented.

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“…The antibacterial effect of zinc oxide is differentiated from biocide agents (like silver) in that it has no environmental effects , and toxicity. − In the literature, there are studies where zinc oxide (ZnO) was added to tellurite and borate glass systems. Also, ZnO has been used to gain antibacterial and photocatalytic feature to glass ceramic systems or different type material systems. − ZnO stimulates oxidative stress via generation of reactive oxygen species (ROS) in bacterial cells, which arrests cell growth and brings about cell lysis with membrane damage . A schematic representation of the antibacterial mechanism to Escherichia coli of glass samples doped with the ZnO sample is shown in Figure .…”

Section: Introductionmentioning

confidence: 99%

Zinc Oxide-Doped Antibacterial Soda Lime Glass Produced as a Glass Container

Demirel

Taygun

2023

ACS Omega

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The aim of this study is to produce and characterize glass materials, which have an enhanced antibacterial property by the conventional melting method. Container glass compositions including different amounts of zinc oxide (ZnO) (5.0, 7.5, and 10.0%) were prepared and melted to be able to obtain the antibacterial glass. The Release and antibacterial tests, which were performed after the melting process, showed that the glass doped with 5% ZnO was the most appropriate composition according to test results (99.82% Escherichia coli inactivation) and its raw materials’ costs. Physical, thermal, and mechanical properties such as thermal expansion coefficient (86.1 × 10–7/°C), density (2.523 g/cm3), refractive index (1.5191), hardness (596 kg/mm2), and elastic modulus (5.84 GPa) of the glass doped with 5% ZnO were determined, and the results showed that the obtained antibacterial glass sample is suitable to be used as a glass container. HighTemperature Melting Observation System studies were performed on the produced antibacterial glass composition, and it was found that the antibacterial glass can be produced in soda lime glass furnaces without changing any furnace design and production parameters. This antibacterial glass can be a remarkable product for the pharmaceutical and food industries.

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Overview of magnesium-ceramic composites: mechanical, corrosion and biological properties

Cited by 84 publications

References 200 publications

Marine Plankton-Derived Whitlockite Powder-Based 3D-Printed Porous Scaffold for Bone Tissue Engineering

Marine Plankton-Derived Whitlockite Powder-Based 3D-Printed Porous Scaffold for Bone Tissue Engineering

Strengthening Mechanisms of Ti–Mg Composite for Biomaterials: A Review

Zinc Oxide-Doped Antibacterial Soda Lime Glass Produced as a Glass Container

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