Overview of endocrine hypertension in children

Metwalley, Kotb Abbass; Farghaly, Hekma Saad

doi:10.1016/j.ppedcard.2022.101581

Cited by 2 publications

(5 citation statements)

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“…Previous studies showed that children with secondary hypertension are more likely to have target organ damage compared to children with primary hypertension especially children with CKD (10). Other studies showed that more than 40% of children with primary hypertensin have LVH at diagnsosis ( 27,28).…”

Section: Discussionmentioning

confidence: 99%

Etiology, treatment and complications of childhood hypertension : A retrospective study

Riyami

2024

Preprint

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Background Hypertension is common in children, with an estimated prevalence of about 2–5%, and is increasing worldwide. This study reports a single-center experience of hypertension in children Methods A retrospective chart review of children aged from one month to 13 years old who were diagnosed with hypertension. Results A total of 129 children were included. Secondary hypertension was seen in 103 (79.8%) patients compared to only 26 (20.2%) who had primary hypertension. Primary hypertension was more common among pre-teen children (50.0%), whereas a higher proportion of the cases with secondary hypertension were aged between 1–5 years. Renal parenchymal diseases were the most common etiology for secondary hypertension, followed by endocrine and then vascular causes. In this study, no significant association was noted between hypertension and obesity. The most common complications of hypertension in these children were cardiovascular complications, followed by neurological complications. Hypertension was only managed by lifestyle modification in 14.7% of children, while the rest were also started on antihypertensive medications. During the last follow-up, 50% of children had improvement in blood pressure readings." Conclusion Secondary hypertension is more common compared to primary hypertension in our patients. The results of this study will increase awareness among pediatricians about the importance of early recognition and management of hypertension. Larger population-based studies are needed to better assess the prevalence, causes, and outcomes of hypertension in our region.

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Section: Discussionmentioning

confidence: 99%

Etiology, treatment and complications of childhood hypertension : A retrospective study

Riyami

2024

Preprint

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“…Гојазна деца и адолесценти имају око три пута већи ризик за настанак хипертензије у односу на децу са нормалном телесном масом, а ризик расте са повећањем количине масног ткива [14]. Повезаност ИТМ и висине крвног притиска може се уочити већ код деце од узраста 2-4 године [15].…”

Section: примарна хипертензијаunclassified

“…Повезаност ИТМ и висине крвног притиска може се уочити већ код деце од узраста 2-4 године [15]. С обзиром да се масно ткиво одскора сматра највећом ендокрином жлездом, неки аутори хипертензију удружену са гојазношћу сврставају у секундарну -ендокрину хипертензију [14]. Значајно је истаћи и да су гојазна деца, као и деца са секундарним обликом хипертензије, посебно она са хроничним бубрежним болестима, у ризику за настанак маскиране хипертензије.…”

Section: примарна хипертензијаunclassified

“…Obese children and adolescents have about three times the risk of developing hypertension compared to children with normal body weight, and the risk increases with an increase in the amount of adipose tissue [14]. The correlation between BMI and blood pressure levels can be observed already in children from the age of 2-4 years [15].…”

Section: примарна хипертензијаmentioning

confidence: 99%

“…The correlation between BMI and blood pressure levels can be observed already in children from the age of 2-4 years [15]. Since fatty tissue is considered the largest endocrine gland as of recently, some authors classify hypertension associated with obesity as secondary -endocrine hypertension [14]. It is also important to note that obese children, as well as children with the secondary form of hypertension, especially those with chronic kidney diseases, are at risk of developing masked hypertension.…”

Section: примарна хипертензијаmentioning

confidence: 99%

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Hypertension in children and adolescents

Damnjanović

2023

Glas javnog zdr

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Until recently, secondary hypertension used to be the most common form of hypertension in the paediatric population. Due to the increasing prevalence of obesity-related hypertension in children and adolescents, the share of secondary hypertension has decreased from 85% to 9%. Today, primary hypertension has become the dominant form of hypertension in the paediatric population. The purpose of this paper is to show the prevalence of various forms of hypertension and the prevalence of primary hypertension in children and adolescents relative to sex, age and body weight category in the General Hospital "Dr. Laza K. Lazarević" in Šabac. In children with secondary hypertension, the impact of body weight was not assessed since an organic cause of hypertension had been identified in these patients. All children from the age of a new-born to the age of 18 years with a diagnosis of hypertension (International Classification of Diseases, tenth revision (IDC-10), code I10-I15) in the period from 1 January 2013 to 31 December 2022 were selected from the medical digital database. This analysis included all children who showed blood pressure values above 95th percentile for age, sex and height in children under 13 and above 120/80 mmHg in children over 13, upon repeated measurements of blood pressure in the General Hospital, who were presumed to have hypertension. These children were referred to further evaluation at tertiary healthcare institutions, where a diagnosis of hypertension was made. Of the 134 children referred to the General Hospital due to elevated blood pressure levels measured in the primary care physician's office, hypertension was diagnosed in almost one in four subjects (24.6%). Primary hypertension was diagnosed in 18 (54.5%), secondary hypertension in 8 (24.2%) and white coat hypertension in 7 (21.2%) children. Primary hypertension was more common in boys (70.6%) than girls (37.5%). Among children with primary hypertension, overweight and obese children represented 66.7% of the group at the time of diagnosis. Statistical data analysis did not find a statistically significant difference in the prevalence of primary hypertension among the body weight or age categories. Since primary hypertension is the most significant and potentially reversible factor for the development of cardiovascular disease, early detection and treatment of primary hypertension in children is crucial in the prevention of cardiovascular disease in adults.

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Overview of endocrine hypertension in children

Cited by 2 publications

References 63 publications

Etiology, treatment and complications of childhood hypertension : A retrospective study

Etiology, treatment and complications of childhood hypertension : A retrospective study

Hypertension in children and adolescents

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