Overview of Collateral Meridian Therapy in Pain Management: A Modified Formulated Chinese Acupuncture

Wong, Chih‐Shung; Yeh, Chun-Chang; Ko, Shan-Chi

doi:10.5772/29916

Cited by 2 publications

(1 citation statement)

References 10 publications

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“…According to the collateral meridian therapy [ 35 , 36 ], needling at PC3 and PC6 on the pericardium meridian allows to divert the obstructed Qi from stomach meridian to pericardium meridian, leading to the amelioration of inflammation and the balance between meridians and immune systems. Therefore, in addition to colonic tissues, we also evaluated the gene expression profiles of spleen in TNBS-induced colitis.…”

Section: Discussionmentioning

confidence: 99%

Electroacupuncture Improves Trinitrobenzene Sulfonic Acid-Induced Colitis, Evaluated by Transcriptomic Study

Chao

et al. 2014

Evidence-Based Complementary and Alternative Medicine

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Inflammatory bowel disease is a chronic colonic inflammation that displays symptoms like diarrhea and weight loss. Acupuncture has been widely accepted by Western countries for the treatment of pain. Here, we analyzed efficacy and mechanism of electroacupuncture (EA) on trinitrobenzene sulfonic acid- (TNBS-) induced colitis in mice. Mice were intrarectally administered with 250 mg/kg TNBS and electroacupunctured at Quze (PC3) and Neiguan (PC6) acupoints, which have been applied for gastrointestinal disorders. Gene expression profiles in colons and spleens were analyzed by microarray for the elucidation of mechanism of EA. Our data showed that EA at PC3 and PC6 improved macroscopic and microscopic features of colitis and the improvement displayed a frequency-dependent manner. Administration of TNBS upregulated the expression of most cytokine genes in colons, while EA downregulated the expression of TNBS-induced cytokine genes. Pathway analysis showed that EA significantly affected inflammatory pathways in colons and immunity-associated pathway in spleens. Immunohistochemical staining further showed that EA decreased the expression of interleukin-1β and nuclear factor-κB. In conclusion, this is the first study reporting the global gene expression profiles of EA on TNBS-induced colitis. Our findings suggested that inflammatory and immunity pathways were involved in the anti-inflammatory mechanism of EA on colitis induced by TNBS.

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Section: Discussionmentioning

confidence: 99%

Electroacupuncture Improves Trinitrobenzene Sulfonic Acid-Induced Colitis, Evaluated by Transcriptomic Study

Chao

et al. 2014

Evidence-Based Complementary and Alternative Medicine

View full text Add to dashboard Cite

show abstract

The therapeutic effect of collateral meridian therapy is comparable to acupoint pressure therapy in treating myofascial pain syndrome

Lee

et al. 2014

Complementary Therapies in Clinical Practice

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Overview of Collateral Meridian Therapy in Pain Management: A Modified Formulated Chinese Acupuncture

Cited by 2 publications

References 10 publications

Electroacupuncture Improves Trinitrobenzene Sulfonic Acid-Induced Colitis, Evaluated by Transcriptomic Study

Electroacupuncture Improves Trinitrobenzene Sulfonic Acid-Induced Colitis, Evaluated by Transcriptomic Study

The therapeutic effect of collateral meridian therapy is comparable to acupoint pressure therapy in treating myofascial pain syndrome

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