Overview of Antioxidant Peptides Derived from Marine Resources: The Sources, Characteristic, Purification, and Evaluation Methods

Abstract

Marine organisms are rich sources of structurally diverse bioactive nitrogenous components. In recent years, numerous bioactive peptides have been identified in a range of marine protein resources, such as antioxidant peptides. Many studies have approved that marine antioxidant peptides have a positive effect on human health and the food industry. Antioxidant activity of peptides can be attributed to free radicals scavenging, inhibition of lipid peroxidation, and metal ion chelating. Moreover, it has also been verified that peptide structure and its amino acid sequence can mainly affect its antioxidant properties. The aim of this review is to summarize kinds of antioxidant peptides from various marine resources. Additionally, the relationship between structure and antioxidant activities of peptides is discussed in this paper. Finally, current technologies used in the preparation, purification, and evaluation of marine-derived antioxidant peptides are also reviewed.

Identification and characterization of a novel antioxidant peptide from feather keratin hydrolysate

“…For example, Dávalos et al (2004) have reported that Cys residues have antioxidative activity, as a Cys -SH group in a peptide acts as an effective hydrogen donor to free radicals (Wu et al 2015). In addition, Pro and Gly residues are commonly found in antioxidative peptides from various sources (López-Barrios et al 2014;Wu et al 2015). Furthermore, a high correlation commonly occurs between reducing power and antioxidative activity in some antioxidative peptides (Zhang et al 2009).…”

“…2b), which are usually related to antioxidative activity (Wu et al 2015). In addition to antioxidative activity, other bioactivities, such as inhibitory activities toward angiotensin I-converting enzyme and dipeptidyl peptidase-IV, have been demonstrated in feather hydrolysate (Fontoura et al 2014).…”

“…Therefore, growing interest is turning to natural antioxidants, especially those from various protein hydrolysates (López-Barrios et al 1997;Wu et al 2015). Many antioxidative peptides have been identified and characterized.…”

Enzyme-Assisted Discovery of Antioxidant Peptides from Edible Marine Invertebrates: A Review

“…In reviews on marine bioactive peptides, enzymatic hydrolysates and antioxidant peptides of fish and their processing by-products often overshadowed those of edible marine invertebrates [18,29,46,47]. In this review, we focus on antioxidant peptides purified and identified from enzymatic hydrolysates of edible marine invertebrates, including those prepared by using in vitro gastrointestinal digestion.…”

Progress in using the drugs based on hydrobionts in treatment of respiratory viral infections and their complications

“…Показано, что пептиды, полученные из гидроли-затов белков морских организмов, например мидий, морского угря, микроводорослей, морских ежей, выступают в качестве потенциальных антиоксидан-тов [30,40,72,74,76]. Антиоксидантная активность биологически активных пептидов связана с нали-чием в их составе гидрофобных аминокислот, не-которых ароматических аминокислот и гистидина.…”