Overlapping with Jack Dunitz

Abstract

The starting point was an overlap with Jack Dunitz in studies on the preferred conformation of the carboxyl group in saturated and unsaturated acids, esters and amides, orientational disorder of the hydrogen‐bonded carboxylic acid dimer in benzoic acid crystal structures, and intramolecular lone pair‐lone pair repulsion between oxygen atoms. The journey described here outlines a search to establish the existence of C−H⋅⋅⋅O hydrogen bonds and engineering cocrystals that incorporate intermolecular lone pair‐lone pair repulsion between oxygen atoms.