Overlapped Fourier coding for optical aberration removal

Horstmeyer, Roarke; Ou, Xiaoze; Chung, Jaebum; Zheng, Guoan; Yang, Changhuei

doi:10.1364/oe.22.024062

Cited by 41 publications

(39 citation statements)

References 45 publications

(69 reference statements)

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“…This work builds on previous nonmicroscopy FP work that are focused on 3D sample refocusing [7] and aberration removal [8]. We show that ASFPM extends these works to demonstrate transmissive mode and reflective mode microscopic imaging.…”

Section: Introductionmentioning

confidence: 64%

“…Previous works have verified that the phase information captured in transmissive mode Fourier ptychography, both by angularly-varying-illumination [4] and aperture scanning [8], is quantitative. Here, for the first time, we demonstrate that the phase information captured in reflective mode Fourier ptychography (ASFPM in this case) is quantitative.…”

Section: Imaging Performancementioning

confidence: 89%

“…While prior work [8] has used an electronically addressable SLM to implement Fourier ptychography, the current setup offers the following 4 key benefits: 1) usage of a reflective LCOS with a much higher fill factor and efficiency than the previously used transmissive liquid crystal display, 2) removal of temporal coherence artifacts, 3) adoption to a microscopic imaging arrangement, and 4) a new capability to operate in a reflective configuration.…”

Section: System Setupmentioning

confidence: 99%

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Aperture scanning Fourier ptychographic microscopy

Ou¹,

Chung²,

Horstmeyer³

et al. 2016

Biomed. Opt. Express

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Fourier ptychographic microscopy (FPM) is implemented through aperture scanning by an LCOS spatial light modulator at the back focal plane of the objective lens. This FPM configuration enables the capturing of the complex scattered field for a 3D sample both in the transmissive mode and the reflective mode. We further show that by combining with the compressive sensing theory, the reconstructed 2D complex scattered field can be used to recover the 3D sample scattering density. This implementation expands the scope of application for FPM and can be beneficial for areas such as tissue imaging and wafer inspection.

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Section: Introductionmentioning

confidence: 64%

Section: Imaging Performancementioning

confidence: 89%

Section: System Setupmentioning

confidence: 99%

See 1 more Smart Citation

Aperture scanning Fourier ptychographic microscopy

Ou¹,

Chung²,

Horstmeyer³

et al. 2016

Biomed. Opt. Express

Self Cite

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show abstract

“…There also have been numerous efforts in improving the Fourier ptychographic (FP) reconstruction by adopting more noise-robust algorithms [15][16][17][18]. Alternative FPM modalities involving aperture scanning instead of angular illuminations were demonstrated, which allowed for imaging the complex field of a thick specimen [19,20] and estimating optical aberrations [21]. Imaging a thick specimen with angular illuminations also became possible by employing the first Born approximation [22] or multislice coherent model [23].…”

Section: Introductionmentioning

confidence: 99%

Wide-field Fourier ptychographic microscopy using laser illumination source

Chung¹,

Lu²,

Ou³

et al. 2016

Biomed. Opt. Express

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Fourier ptychographic (FP) microscopy is a coherent imaging method that can synthesize an image with a higher bandwidth using multiple low-bandwidth images captured at different spatial frequency regions. The method's demand for multiple images drives the need for a brighter illumination scheme and a high-frame-rate camera for a faster acquisition. We report the use of a guided laser beam as an illumination source for an FP microscope. It uses a mirror array and a 2-dimensional scanning Galvo mirror system to provide a sample with plane-wave illuminations at diverse incidence angles. The use of a laser presents speckles in the image capturing process due to reflections between glass surfaces in the system. They appear as slowly varying background fluctuations in the final reconstructed image. We are able to mitigate these artifacts by including a phase image obtained by differential phase contrast (DPC) deconvolution in the FP algorithm. We use a 1-Watt laser configured to provide a collimated beam with 150 mW of power and beam diameter of 1 cm to allow for the total capturing time of 0.96 seconds for 96 raw FPM input images in our system, with the camera sensor's frame rate being the bottleneck for speed. We demonstrate a factor of 4 resolution improvement using a 0.1 NA objective lens over the full camera field-of-view of 2.7 mm by 1.5 mm. References and links1. G. Zheng, R. Horstmeyer, and C. Yang, "Wide-field, high-resolution Fourier ptychographic microscopy," Nat. Photonics 7(9), 739-745 (2013). 2. X. Ou, R. Horstmeyer, C. Yang, and G. Zheng, "Quantitative phase imaging via Fourier ptychographic microscopy,"Opt. Lett. 38(22), 4845-4848 (2013). 3. R. Hegerl, W. Hoppe, "Dynamic theory of crystal structure analysis by electron diffraction in the inhomogeneous primary radiation wave field," Ber. Bunsenges. Phys. Chem. 74(11), 1148-1154 (1970). 4. X. Ou, R. Horstmeyer, G. Zheng, and C. Yang, "High numerical aperture Fourier ptychography: principle, implementation and characterization," Opt. Express 23(3), 3472-3491 (2015). 5. J. Chung, X. Ou, R. P. Kulkarni, and C. Yang, "Counting White Blood Cells from a Blood Smear Using Fourier Ptychographic Microscopy," PloS ONE 10(7), e0133489 (2015). 6. S. Dong, K. Guo, P. Nanda, R. Shiradkar, and G. Zheng, "FPscope: a field-portable high-resolution microscope using a cellphone lens," Biomed. Opt. Express 5(10), 3305-3310 (2014). 7. K. Guo, Z. Bian, S. Dong, P. Nanda, Y. M. Wang, and G. Zheng, "Microscopy illumination engineering using a low-cost liquid crystal display," Biomed. Ultramicroscopy 109(10), 1256-1262 (2009). 11. X. Ou, G. Zheng, and C. Yang, "Embedded pupil function recovery for Fourier ptychographic microscopy," Opt.Express 22(5), 4960-4972 (2014). 12. A. Williams, J. Chung, X. Ou, G. Zheng, S. Rawal, Z. Ao, R. Datar, C. Yang, and R. Cote, "Fourier ptychographic microscopy for filtration-based circulating tumor cell enumeration and analysis," J.

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“…The state-of-the-art solution to this problem is to keep the illumination angle constant, but scan the aperture directly across the back focal plane [14] or use a SLM to achieve the same effect [15], and as shown in Fig. 2(b1).…”

Section: Introductionmentioning

confidence: 99%