Overexpression of Tat-interacting protein 30 inhibits the proliferation, migration, invasion and promotes apoptosis in bladder cancer cells

Li, Yeping; Cai, Bing; Chen, Sansan; Fu, Xiafei; Pang, Xiang; Qi, Honggang; Tan, Wanlong

doi:10.4103/0973-1482.206869

J Can Res Ther

2018

DOI: 10.4103/0973-1482.206869

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Overexpression of Tat-interacting protein 30 inhibits the proliferation, migration, invasion and promotes apoptosis in bladder cancer cells

Yeping Li¹,

Bing Cai²,

Sansan Chen³

et al.

Abstract: These results suggest that TIP30, as a tumor suppressor in the bladder cancer, might be served as a target in cancer therapies in the future.

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Utility of a Metabolic-Associated Nomogram to Predict the Recurrence-Free Survival of Stage I Cervical Cancer

Zhang

et al. 2021

Future Oncol.

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Aims: To identify metabolism-associated genes (MAGs) that serve as biomarkers to predict prognosis associated with recurrence-free survival (RFS) for stage I cervical cancer (CC). Patients & methods: By analyzing the Gene Expression Omnibus (GEO) database for 258 cases of stage I CC via univariate Cox analysis, LASSO and multivariate Cox regression analysis, we unveiled 11 MAGs as a signature that was also validated using Kaplan–Meier and receiver operating characteristic analyses. In addition, a metabolism-related nomogram was developed. Results: High accuracy of this signature for prediction was observed (area under the curve at 1, 3 and 5 years was 0.964, 0.929 and 0.852 for the internal dataset and 0.759, 0.719 and 0.757 for the external dataset). The high-risk score group displayed markedly worse RFS than did the low-risk score group. The indicators performed well in our nomogram. Conclusions: We identified a novel signature as a biomarker for predicting prognosis and a nomogram to facilitate the individual management of stage I CC patients.

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Utility of a Metabolic-Associated Nomogram to Predict the Recurrence-Free Survival of Stage I Cervical Cancer

Zhang

et al. 2021

Future Oncol.

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Overexpression of Tat-interacting protein 30 inhibits the proliferation, migration, invasion and promotes apoptosis in bladder cancer cells

Abstract: These results suggest that TIP30, as a tumor suppressor in the bladder cancer, might be served as a target in cancer therapies in the future.

Cited by 1 publication

References 0 publications

Utility of a Metabolic-Associated Nomogram to Predict the Recurrence-Free Survival of Stage I Cervical Cancer

Utility of a Metabolic-Associated Nomogram to Predict the Recurrence-Free Survival of Stage I Cervical Cancer

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