“…Researchers studying hypertensive disease progression have used different approaches to transfer these cells, including negative selection of T cells using magnetic bead sorting (Barhoumi et al, 2011;Chen et al, 2018b;Guzik et al, 2007;Hoch et al, 2009;Iulita et al, 2019;Ji et al, 2014;Kinsey et al, 2009;Kvakan et al, 2009;Marvar et al, 2010;Mian, Barhoumi, Briet, Paradis, & Schiffrin, 2016;Pons et al, 2013;Senchenkova, Russell, Kurmaeva, Ostanin, & Granger, 2011;Trott et al, 2014;Wu et al, 2014Wu et al, , 2016, positive selection for T-regulatory cells (Barhoumi et al, 2011;Cornelius et al, 2015;Kasal et al, 2012;Mian et al, 2016;Turner et al, 2010) or flow-assisted cell (FAC) sorting (Chen et al, 2018b;Kassan, Galan, Partyka, Trebak, & Matrougui, 2011;Kvakan et al, 2009;Yang et al, 2008). In addition, cell culture techniques have been used to enrich specific T-cell subsets before transfer (Chen et al, 2018b;Hayakawa et al, 2000;McRae, Russell, Chia, & Dwyer, 2013;Meyers, Tomaszewski, Glass, & Chen, 1998;Wallace et al, 2012;Wang et al, 2006). Important work has demonstrated that the sex of the donor and of the recipient can influence the hypertensive phenotype of the recipient, which has revealed an integral role of sex hormones in the development of hypertension (Ji et al, 2014;Pollow et al, 2014).…”