“…For example, GPR40 played an important role in regulating glucose-stimulated insulin secretion and glucose homeostasis in a long-term study involving normal and diabetic mice [10] and, over an extended period, it improved insulin secretory responses to FFAs and glucose tolerance in mice fed high fat original article DIABETES, OBESITY AND METABOLISM diets [17]. For example, GPR40 played an important role in regulating glucose-stimulated insulin secretion and glucose homeostasis in a long-term study involving normal and diabetic mice [10] and, over an extended period, it improved insulin secretory responses to FFAs and glucose tolerance in mice fed high fat original article DIABETES, OBESITY AND METABOLISM diets [17].…”