Overcoming the hurdles and establishing a haematopoietic stem cell transplant centre in a resource poor setting: an example from Dhaka, Bangladesh

Mahfuz, Huque; Hossain, Mohammad Enayet; Uddin, Mohammad M.; Karim, Mostafil; Wright, Josh; Joyce, Kevin; Islam, Amin

doi:10.1111/bjh.17532

Cited by 2 publications

(2 citation statements)

References 6 publications

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“…A successful transplantation program's foundation is built on the experience of medical, nursing, and laboratory staff, hospital support, and effective leadership. 10,35 The biggest challenge to establishing the HSCT program in Ethiopia is the lack of transplant doctors, except for a few hematologists, and an abundant middle-level workforce; internists, lab technicians, nurses, and pharmacists.…”

Section: Human Resource Developmentmentioning

confidence: 99%

Why and How Should Ethiopia Establish a Stem Cell Transplant Service? A Review Article

Mekonnen¹,

Farris²

2023

BTT

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Ethiopia is attempting to reduce cancer-related morbidity and mortality through a strategic national cancer control plan but according to Globocan 2020, hematologic malignancies particularly leukemia and non-Hodgkin's lymphoma rank among the top five leading causes of new cancer incidence and cause of death among all age groups in both sexes. Hematopoietic stem-cell transplantation (HSCT) is an advanced treatment modality that makes the only effective treatment for cancer and non-cancer-related hematologic diseases unresponsive to conventional therapy. Patients who need stem cell transplants must travel to abroad countries to get the treatment. Meanwhile, the Ethiopian National Specialty and Subspecialty Roadmap sets the goal of establishing HSCT centers in 2020-2029 GC, yet leaders and planners must start taking steps to put the setup in place. Setting up an HSCT facility is challenging for developing countries due to the high costs, limited infrastructure, and need for intensive medical staff training; however, several nations have been able to start successful stem cell transplant programs. This review summarizes the basic steps and requirements of the program in light of guidelines recommendations and lessons learned from other developing countries. It also highlights possible cost-effective opportunities, bottlenecks, and areas that will require work and investment to make the objective reality in Ethiopia.Provides key information to assist administrators and policymakers to set priorities in planning and making informed decisions to establish and maintain the service.

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Section: Human Resource Developmentmentioning

confidence: 99%

Why and How Should Ethiopia Establish a Stem Cell Transplant Service? A Review Article

Mekonnen¹,

Farris²

2023

BTT

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“…1,000 2,000 3,000 4,000 5,000 6,000 N All HCT centers even within RCS will ultimately need to offer the full range of HCT services for pediatric and adult patients depending on the indications for the patients being served. However, the most critical issue in determining the focus and direction of any new HCT service is the training and experience of the lead transplant physician and the access to various support infrastructure, as exemplified in a recent report from Bangladesh and Nepal (Mahfuz et al 2021;Poudyal et al 2022). While it would be desirable for HCT services to be offered in governmentfunded public hospitals, this has not been a successful model in many RCS where paradoxically HCT rates are higher when services are offered in private hospitals as reported from Latin America (Jaimovich et al 2021).…”

Section: Introductionmentioning

confidence: 99%

Feasibility and Experiences of HCT in Resource-Constrained Settings

Srivastava,

Duarte,

Faulkner

2024

The EBMT Handbook

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Even though hematopoietic cell transplant (HCT) has been in vogue for more than six decades as a curative therapy for many hematological disorders, with increasing trends in all parts of the world (Fig. 69.1), the density of HCT services is low and access to existing services remain an unmet need in the resource-constrained settings (RCSs) of low- and middle-income countries (LMICs) (Niederwieser et al. 2022). The silver lining though is that within these limitations, there are several examples of high-quality HCT services functioning in several countries, some with full national/international accreditation showing that even in those circumstances this is possible (Damodar et al. 2021). The goal of this chapter will be to discuss how good HCT services may be established and sustained in RCSs (Pasquini et al. 2019; Faulkner et al. 2021).

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Overcoming the hurdles and establishing a haematopoietic stem cell transplant centre in a resource poor setting: an example from Dhaka, Bangladesh

Cited by 2 publications

References 6 publications

Why and How Should Ethiopia Establish a Stem Cell Transplant Service? A Review Article

Why and How Should Ethiopia Establish a Stem Cell Transplant Service? A Review Article

Feasibility and Experiences of HCT in Resource-Constrained Settings

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