Overcoming Barriers in Glioblastoma—Advances in Drug Delivery Strategies
Esther ter Linden,
Erik R. Abels,
Thomas S. van Solinge
et al.
Abstract:The world of cancer treatment is evolving rapidly and has improved the prospects of many cancer patients. Yet, there are still many cancers where treatment prospects have not (or hardly) improved. Glioblastoma is the most common malignant primary brain tumor, and even though it is sensitive to many chemotherapeutics when tested under laboratory conditions, its clinical prospects are still very poor. The blood–brain barrier (BBB) is considered at least partly responsible for the high failure rate of many promis… Show more
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