Overall volumetric mass transfer coefficient in a modified reversed flow jet loop bioreactor with low density particles

Prasad, K. Yagna; Ramanujam, T. K.

doi:10.1007/bf01767469

Cited by 4 publications

(4 citation statements)

References 21 publications

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“…4A, Section 2.4). For the JLR the absolute values of the obtained k L a dyn values (k L a dyn (P L /V, u g ) fit to the results obtained by correlation published by Jamshidi et al [37] and Prasad and Ramanujam [36] (Eq. (9)).…”

Section: Comparison Of Str (B1) and Retrofitted Jlr (A1)supporting

confidence: 72%

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Impact of nozzle operation on mass transfer in jet aerated loop reactors. Characterization and comparison to an aerated stirred tank reactor

Weber

Schaepe

Freyer

et al. 2018

Engineering in Life Sciences

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The impact of mass transfer on productivity can become a crucial aspect in the fermentative production of bulk chemicals. For highly aerobic bioprocesses the oxygen transfer rate (OTR) and productivity are coupled. The achievable space time yields can often be correlated to the mass transfer performance of the respective bioreactor. The oxygen mass transfer capability of a jet aerated loop reactor is discussed in terms of the volumetric oxygen mass transfer coefficient kLa [h−1] and the energetic oxygen transfer efficiency E [kgO2 kW−1 h−1]. The jet aerated loop reactor (JLR) is compared to the frequently deployed aerated stirred tank reactor. In jet aerated reactors high local power densities in the mixing zone allow higher mass transfer rates, compared to aerated stirred tank reactors. When both reactors are operated at identical volumetric power input and aeration rates, local kLa values up to 1.5 times higher are possible with the JLR. High dispersion efficiencies in the JLR can be maintained even if the nozzle is supplied with pressurized gas. For increased oxygen demands (above 120 mmol L−1 h−1) improved energetic oxygen transfer efficiencies of up to 100 % were found for a JLR compared to an aerated stirred tank reactor operating with Rushton turbines.

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Section: Comparison Of Str (B1) and Retrofitted Jlr (A1)supporting

confidence: 72%

“…For the JLR the k L a value was correlated using the Sherwood number (Sh), the respective diffusion coefficient (D AB ) and a length scale expressed as diameter (D R ) of the section available for co-current flow of gas and liquid [36,37].…”

Section: Dynamic K L A-measurements Apparatus A1 and B1mentioning

confidence: 99%

Impact of nozzle operation on mass transfer in jet aerated loop reactors. Characterization and comparison to an aerated stirred tank reactor

Weber

Schaepe

Freyer

et al. 2018

Engineering in Life Sciences

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“…. The Sherwood number is the ratio of effective mass transfer to diffusive mass transfer and a variety of correlations for various reactor types and flow regimes is available in the literature . Most commonly they are expressed as a function of the two dimensionless parameters Schmidt ( Sc ) and Reynolds number ( Re ) depicted in Eqs.…”

Section: Resultsmentioning

confidence: 99%

Considerations on film reactivity in the aqueous biphasic hydroformylation

2017

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In experiments and kinetic models it was shown that the reaction rate of the biphasic aqueous hydroformylation of 1octene is linear dependent on the created interfacial area. This phenomenon is directly linked to the question whether the reaction takes place in the bulk phase and is mass transfer limitation or at the surface which would mean an increase of reaction space. To evaluate the place of reaction a mass transfer analysis has been carried out. No mass transfer limitation for the gaseous components carbon monoxide and hydrogen as well as the olefin 1-octene was determined for the aqueous catalyst phase by calculating the Hatta numbers. With this observation it is possible to exclude the mass transfer as a potential influence and hence the aqueous bulk as the place of reaction. Thus the reaction is most probably surface active. This can be either explained the increase in film volume fraction where non-polar substrate as well as polar catalyst complex is present or through an increased catalyst concentration at the surface through dipole moment fluctuations.Experimental Materials 1-Hexene (971%), 1-octene (991%), and 1-decene (95%) were purchased from Acros Organics; 1-dodecene was V tot 5 0.001 m 3 , u 5 0.6, c Rh 5 0.5 mol m 23 aq , P/Rh 5 10, precursor 5 [Rh(cod)Cl]2, T 5 353.15 K, pH 5 5.5, p tot 5 8 MPa, p H2 /p CO 5 1, t 5 1.5 h. 5 163 V tot 5 0.001 m 3 , u 5 0.6, c Rh 5 0.5 mol m 23 aq, P/Rh 5 10, precursor 5 [Rh(cod)Cl]2, T 5 353.15 K, pH 5 5.5, p tot 5 8 MPa, p H2 /p CO 5 1, t 5 1.5 h. 5 V tot 5 0.001 m 3 , u 5 0.6, c Rh 5 0.5 mol m 23 aq, P/Rh 5 10, precursor 5 [Rh(cod)Cl]2, T 5 353.15 K, pH 5 5.5, p tot 5 8 MPa, p H2 /p CO 5 1, t 5 1.5 h. 1HX 5 1-hexene, 1OC 5 1-octene, 1DC 5 1-decene.V tot 5 0.001 m 3 , u 5 0.6, c Rh 5 0.5 mol m 23 aq, P/Rh 5 10, precursor 5 [Rh(cod)Cl]2, T 5 353.15 K, pH 5 5.5, p tot 5 8 MPa, p H2 /p CO 5 1, t 5 1.5 h.

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“…The draft tube diameter is adjusted to achieve maximal mass transfer in the reactor [45][46][47][48]. The design parameters used in this work are defined by Equations 6-9:…”

Section: Experimental Reactor Designmentioning

confidence: 99%

Enhancing mass transport to accelerate photoreactions and enable scale-up

Gaulhofer,

Metzger,

Peschl

et al. 2023

Preprint

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The importance of mixing in photoreactors along the direction of light propagation for competitive photochemical reactions is experimentally demonstrated in the MISCOP mini-plant photoreactor. The installation of customized static mixers improved the photonic efficiency of the photochemical ring-opening isomerization of 1,3,3-trimethylindolino-6'-nitrobenzopyrylospirane by a factor of 2.4, which could be related to the improved mass transport. This knowledge enables future scaling of photoreactions in multi-lamp reactors.

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Overall volumetric mass transfer coefficient in a modified reversed flow jet loop bioreactor with low density particles

Abstract: Experiments were conducted using glass beads and Hr m low-density particles such as polyurethane and polystyrene which are comparable to bioparticles found in biological applications to evaluate the overall volumetric mass transfer KL m scoefficient (KLa) List of symbols

Cited by 4 publications

References 21 publications

Impact of nozzle operation on mass transfer in jet aerated loop reactors. Characterization and comparison to an aerated stirred tank reactor

Impact of nozzle operation on mass transfer in jet aerated loop reactors. Characterization and comparison to an aerated stirred tank reactor

Considerations on film reactivity in the aqueous biphasic hydroformylation

Enhancing mass transport to accelerate photoreactions and enable scale-up

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