Overactive intrathyroid parathyroid glands

Billings, P. J.; Milroy, E. J. G.; Heath, David A.; Bainbridge, E. T.; Bainbridge, A. D.

doi:10.1002/bjs.1800690826

Cited by 2 publications

(3 citation statements)

References 1 publication

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“…Most supposed intrathyroid glands are in fact sub-capsular, sunk into the surface of the thyroid, and may be found by a careful dissection of the thyroid surface beneath the fascia1 covering of the gland. We have found that the incidence of true intrathyroid parathyroid glands in all our parathyroid patients is 4.9 per cent (12). Five of the 8 inferior adenomas were found particular value in reoperative parathyroid surgery if 3 glands have been excised previously leaving one abnormal gland.…”

Section: Surgical Failures Of J R S T Operationmentioning

confidence: 60%

Reoperative parathyroid surgery

Billings

Milroy

1983

Journal of British Surgery

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The increasing recognition of hypercalcaemia caused by primary hyperparathyroidism has led to a rise in the number of failed parathyroid exploration. We report a series of 37 parathyroid re-explorations on 33 patients with persistent hypercalcaemia following the failure of their previous parathyroid surgery. Of these patients, 27 have been cured of their hypercalcaemia but 7 are permanently hypocalcaemic. The results of the parathyroid localization tests used in this series are described, and the difficulties of reoperative parathyroid surgery are discussed. The reasons for failure of the original operations are analysed. Many are avoidable. Based on our experience strategies are described for parathyroid localization and reoperative surgery.

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Section: Surgical Failures Of J R S T Operationmentioning

confidence: 60%

Reoperative parathyroid surgery

Billings

Milroy

1983

Journal of British Surgery

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“…The smaller the graft, the more the chances of survival by imbibition. Billings and Milroy ( 85 ) have reported successful transplants in which the harvested parathyroid tissue was minced in iced Waymouth’s tissue culture medium. The resulting suspension was transplanted into the deltoid and brachioradialis muscles, by means of placement into pockets as well as by injection into the muscles.…”

Section: Methods Of Transplantationmentioning

confidence: 99%

“…The advantage of employing the sternocleidomastoid is that another incision can be avoided. Successful PTAT into the brachioradialis has also been reported (78,79,85). While it requires a separate incision, it is much easier to assess functioning of the graft.…”

Section: Site For Transplantationmentioning

confidence: 97%

Preservation of parathyroid glands during thyroid and neck surgery

Rao

Moinuddin

et al. 2023

Front. Endocrinol.

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The parathyroid glands are situated in close proximity to the thyroid gland. They have an important endocrine function maintaining calcium and phosphate homeostasis in the body by the secretion of parathormone (PTH), which is responsible for this function. The parathyroid glands are commonly damaged during thyroid surgeries. This could lead to transient or permanent hypoparathyroidism in 30% of cases. Preservation of the parathyroid glands, is an important and integral part of thyroidectomy and other surgical interventions in the neck. The main principle underlying this is a thorough understanding of parathyroid anatomy in relation to the thyroid gland and other important structures in the area. There can also be significant variation in the anatomical location of the glands. Various techniques and methods have been described for parathyroid preservation. They include intraoperative identification utilizing indocyanine green (ICG) fluorescence, carbon nanoparticles, loupes, and microscopes. The techniques of surgery (meticulous capsular dissection), expertise, central compartment neck dissection, preoperative vitamin D deficiency, extent and type of thyroidectomy are the risk factors associated with damaged thyroids, inadvertent parathyroidectomy and subsequent hypoparathyroidism. Parathyroid Autotransplantation is a treatment option for inadvertent parathyroidectomy. Ultimately, the best way to assure normal parathyroid function is to preserve them in situ intraoperatively undamaged.

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Overactive intrathyroid parathyroid glands

Cited by 2 publications

References 1 publication

Reoperative parathyroid surgery

Reoperative parathyroid surgery

Preservation of parathyroid glands during thyroid and neck surgery

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