Over view of major traumatic injury in Australia––Implications for trauma system design

Cameron, Peter; Fitzgerald, Mark; Curtis, Kate; McKie, Emily; Gabbe, Belinda; Earnest, Arul; Christey, Grant; Clarke, Chris; Crozier, John; Dinh, Michael; Ellis, Daniel Y; Howard, Teresa; Joseph, Anthony; McDermott, Kathleen; Matthew, Joseph; Ogilvie, Rebekah; Pollard, Cliff; Rao, Sudhakar; Reade, Michael C.; Rushworth, Nick; Zalstein, Salomon

doi:10.1016/j.injury.2019.09.036

Cited by 22 publications

(13 citation statements)

References 16 publications

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“…The rate of HDFN was modelled using published data from the following countries: Australia, Brazil, China, India, Japan, Nigeria, Trinidad and Tobago and United States [7–41]. Critical assumptions used in the model, that is, the computation of HDFN risk based on the independent variables employed, and supporting literature are provided in Table 1.…”

Section: Methodsmentioning

confidence: 99%

“…This 21% alloimmunization rate was modelled using a binomial random variate and was utilized for all of the countries simulated. 14Á8 [17] 24Á3 [33] 20Á5 [41] 33Á3 [21] 23.8 [30] 31.5 [38] 33.5 [14] 18.5 [35] Anti-D immunization rate (%) [23,24,40 23Á3 (27-month IPI) [18] 30Á2 [25] 25Á8 [36] 32.6 [12] 21.6 (15-month IPI) [15] 24.2 (24-month IPI) [32] 29.4 [7] 3rd birth 33Á2 (24-month IPI) [32] 25Á5 (27-month IPI) [18] 31Á4 [25] 27Á4 [36] 33.6 [12] 22.9 (15-month IPI) [15] 26.2 (24-month IPI) [32] 30.6 [7] 4th birth 35Á2 (24-month IPI) [32] 27Á7 (27-month IPI) [18] 33Á4 (24-month IPI) [32] 29Á0 [36] 35.6 (24-month IPI) [32] 24.2 (15-month IPI) [15] 28.2 (24-month IPI) [32] 31.7 [7] 5th birth 37Á2 (24-month IPI) [32] 29Á9 (27-month IPI) [18] 35Á4 (24-month IPI) [32] 31Á0 [36] 37.6 (24-month IPI) [32] 25.5 (15-month IPI) [15] 30.2 (24-month IPI) [32] 32.7 [7] 6th birth 39Á2 (24-month IPI) [32] 32Á1 (27-month IPI) [18] 37Á4 (24-month IPI)…”

Section: Derivation Of Anti-rh(d) Alloimmunization Ratementioning

confidence: 99%

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The risk to future pregnancies of transfusing Rh(D)‐negative females of childbearing potential with Rh(D)‐positive red blood cells during trauma resuscitation is dependent on their age at transfusion

et al. 2021

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Background A risk assessment model for predicting the risk of haemolytic disease of the fetus and newborn (HDFN) in future pregnancies following the transfusion of Rh(D)‐positive red blood cell (RBC)‐containing products to females of childbearing potential (FCP) was developed, accounting for the age that the FCP is transfused in various countries. Methods The HDFN risk prediction model included the following inputs: risk of FCP death in trauma, Rh(D) alloimmunization rate following Rh(D)‐positive RBC transfusion, expected number of live births following resuscitation, probability of carrying an Rh(D)‐positive fetus, the probability of HDFN in an Rh(D)‐positive fetus carried by an alloimmunized mother. The model was implemented in Microsoft R Open, and one million FCPs of each age between 18 and 49 years old were simulated. Published data from eight countries, including the United States, were utilized to generate country‐specific HDFN risk estimates. Results The risk predictions showed similar characteristics for each country in that the overall risk of having a pregnancy affected by HDFN was higher if the FCP was younger when she received her Rh(D)‐positive transfusion than if she was older. In the United States, the overall risk of HDFN if the FCP was transfused at age 18 was 3·4% (mild: 1·20%, moderate: 0·45%; severe: 1·15%; IUFD: 0·57%); the risk was approximately 0% if the FCP was 43 years or older at the time of transfusion. Conclusion This model can be used to predict HDFN outcomes when establishing transfusion policies as it relates to the administration of Rh(D)‐positive products for massively bleeding FCPs.

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Section: Methodsmentioning

confidence: 99%

Section: Derivation Of Anti-rh(d) Alloimmunization Ratementioning

confidence: 99%

The risk to future pregnancies of transfusing Rh(D)‐negative females of childbearing potential with Rh(D)‐positive red blood cells during trauma resuscitation is dependent on their age at transfusion

et al. 2021

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“…32 The Australia New Zealand Trauma Registry (ATR) has enabled Australia to establish a robust method of assessing the system of major trauma care across Australia. 33 A registry of concussion could build upon these strong foundations, capitalising on existing infrastructure to enhance efficiencies. Other registries, such as the Australian Spinal Cord Injury Register (ASCIR) which records incident cases of spinal cord injury treated in Australian Spinal Units, 34 enable measurements of injury incidence, study of circumstances and mechanisms of injury.…”

Section: A Tbi Registrymentioning

confidence: 99%

Post-concussion states: How do we improve our patients’ outcomes? An Australian perspective

Thomas

Fitzgerald

Cowen

2020

Journal of Concussion

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There is limited data surrounding incidence and prevalence of concussion and the resulting post-concussion states. This creates difficulty when investigating ways to optimise patient management. It is proposed that a registry of patients presenting with symptoms and signs after a concussion, as part of a large scale TBI registry across Australia, would provide a starting point for future research with a view to improving the outcomes of patients experiencing symptoms and signs after concussion.

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“…Injury is the leading cause of death for Australians in the first four decades of life 1 and Tasmanians suffer worse outcomes than the national average for several categories of trauma 2 . Previously, the Australian Quality Improvement Program (AusTQIP) has called for targeted prevention strategies based upon accurate characterisation of the types, causes, geographic distribution and social context of injury 3 . In 2020, Tasmania responded to this public health imperative by commissioning the Tasmanian Trauma Registry (TTR), which in April 2021 submitted its first 12 months of data to the Australia New Zealand Trauma Registry (ATR).…”

Section: Introductionmentioning

confidence: 99%

“…2 Previously, the Australian Quality Improvement Program (AusTQIP) has called for targeted prevention strategies based upon accurate characterisation of the types, causes, geographic distribution and social context of injury. 3 In 2020, Tasmania responded to this public health imperative by commissioning the Tasmanian Trauma Registry (TTR), which in April 2021 submitted its first 12 months of data to the Australia New Zealand Trauma Registry (ATR). This Perspective outlines lessons learned through the TTR development process.…”

Section: Introductionmentioning

confidence: 99%

Learning from the first 12 months of the Tasmanian Trauma Registry

Mahoney

Collins

Hawkins

2022

Emerg Medicine Australasia

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The Tasmanian Trauma Registry began collecting data in April 2020 and in April 2021 the first 12 months' data were submitted to the Australia New Zealand Trauma Registry. In this perspective, we share the lessons we have learned in establishing a trauma registry and acknowledge how important support from the broader trauma community has been in allowing Tasmania to participate in national benchmarking and quality assurance processes.

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Over view of major traumatic injury in Australia––Implications for trauma system design

Cited by 22 publications

References 16 publications

The risk to future pregnancies of transfusing Rh(D)‐negative females of childbearing potential with Rh(D)‐positive red blood cells during trauma resuscitation is dependent on their age at transfusion

The risk to future pregnancies of transfusing Rh(D)‐negative females of childbearing potential with Rh(D)‐positive red blood cells during trauma resuscitation is dependent on their age at transfusion

Post-concussion states: How do we improve our patients’ outcomes? An Australian perspective

Learning from the first 12 months of the Tasmanian Trauma Registry

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