Over-expression of KRT8 is associated with invasion of non-functioning pituitary adenomas
Yong Chen,
QingXiu Li,
XuRi Song
et al.
Abstract:Objectives
This study aimed to investigate the correlation between KRT8 and non-functioning pituitary adenomas (NFPAs).
Methods
Tumor tissues from fifty NFPAs (comprising twenty-nine cases of invasive NFPAs and twenty-one cases of noninvasive NFPAs) obtained from transsphenoidal surgery were utilized. Gene expression levels and protein expression levels were assessed using qRT-PCR and western blot techniques in both invasive and non-invasive NFPAs tumor tissue samples. The level of KRT8 was downregulated in … Show more
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