Ovarian tumors in children and adolescents: A series of 41 cases

Peroux, É.; Franchi‐Abella, Stéphanie; Sainte-Croix, D.; Canale, Sandra; Gauthier, F.; Martelli, Hélène; Pariente, D; Adamsbaum, C.

doi:10.1016/j.diii.2014.07.001

Cited by 43 publications

(36 citation statements)

References 32 publications

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“…The occurrence of true PP in girls below one year of age is rare, and most cases described in the literature were due to an ovarian neoplasm [7,8,11,12]. To the best of our knowledge, ours is the first infant to develop PP due to an autonomous ovarian cyst.…”

Section: Discussionmentioning

confidence: 78%

“…Autonomous functional ovarian follicular cysts are the most common cause of PPP in girls [1,3]. Ovarian neoplasms are rare in children and include germ cell tumours, surface epithelial stromal tumours, sex cord-stromal tumours (SCSTs), and miscellaneous tumours such as gonadoblastoma, malignant lymphoma, small cell carcinoma, and soft-tissue tumours [7,8]. The oestrogen-producing ovarian tumours such as SCSTs and gonadoblastomas may cause isosexual PPP as an initial manifestation [7,8].…”

Section: Discussionmentioning

confidence: 99%

“…The decision for surgical removal was taken primarily because of suspicion of malignancy because the exact nature of the ovarian mass could not be ascertained after initial investi-gations, and because of features of ovarian torsion on imaging. a rapid progression of pubertal changes with height acceleration and BA advancement at presentation favoured a malignant mass [7,8]. However, a conservative approach may be preferred in cases of ovarian cysts because surgical treatment does not always prevent recurrence [1,3].…”

Section: Discussionmentioning

confidence: 99%

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An intriguing case of precocious puberty due to an ovarian mass in an infant

Dayal

Seetharaman

Prema

et al. 2019

pedm

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We present a rare occurrence of precocious puberty (PP) probably due to an autonomous ovarian cyst in a 15-month-old girl who presented to us with growth spurt, breast and pubic hair development, and vaginal bleeding over the last few months. The clinical presentation was suggestive of central precocious puberty (CPP). However, the rapid progression of pubertal changes and occurrence of menarche at breast Tanner stage 2 indicated peripheral precocious puberty (PPP). Due to uncertainty of clinical diagnosis, investigations were conducted for CPP as well as PPP. The basal and peak stimulated LH concentrations were < 0.3 IU/l and < 2 IU/l, respectively, indicating PPP. However, the peak LH : FSH ratio was > 1, which is consistent with CPP. Abdominal imaging revealed an ovarian mass, which was laparoscopically excised, but the true nature of the mass could not be ascertained because the excised specimen showed only haemorrhage and features of ovarian torsion on histopathological examination. Regression of pubertal development occurred over a three-month period postoperatively.

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Section: Discussionmentioning

confidence: 78%

Section: Discussionmentioning

confidence: 99%

Section: Discussionmentioning

confidence: 99%

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An intriguing case of precocious puberty due to an ovarian mass in an infant

Dayal

Seetharaman

Prema

et al. 2019

pedm

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“…Jinekolojik maligniteler tüm çocukluk çağı kanserlerinin %2'sini oluşturmaktadır. Beş yaş altında ender olarak malign over lezyonu saptanmakla birlikte, 15 yaş altı çocuklarda over tümörü görülme sıklığı 2,6/100.000 olarak bildirilmiştir (1) . Over dokusu 50 ayrı kitlesel oluşumun gelişebileceği karmaşık embriyolojik, histolojik ve fizyolojik özelliklere sahiptir.…”

Section: Genel Bilgilerunclassified

“…Çocukluk çağı over tümörleri epitelyal hücreli, germ hücreli ve seks kord stromal tümörler olarak 3 ana grupta değerlendirilir (1) . Bu gruplar dışında ender olarak hematolojik malignitelerin metastazlarına bağlı tutulumlar görülebilir.…”

Section: Genel Bilgilerunclassified

Ovarian tumors: General, surgical and oncological aspects

Kırlı¹,

Ekinci²

2016

tcdd

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Çocukluk çağı jinekolojik kitlelerin çoğu over kaynaklıdır ve bu lezyonların yaklaşık %10'u malign karakterdedir. En sık rastlanan over tümörleri germ hücre kökenlidir. Ameliyat öncesi görüntüleme yöntemleri ve tümör belirteçlerinin değerlendirmesi sonucu seçilmiş olgularda organ koruyucu yaklaşımla tümör cerrahisinin basamakları eksiksiz olarak tamamlanabilir ve tümörün histolojik özelliklerine göre düzenlenecek medikal tedavi ile çocukluk çağı over tümörlerinde sağ kalım oranı yüksek, doğurganlığın korunması kabul edilir düzeyde tutulabilir.

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Pediatric, adolescent, and young adult breast and reproductive tumors

Harris

Rowell

Jayasinghe

et al. 2022

Pediatric Blood & Cancer

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Tumors of the breast and reproductive organs that occur in children, adolescents, and young adults (AYA) have different biological features and can present special challenges. Although prognosis for these tumors is generally favorable, the long‐term effects of treatment can be debilitating. Treatments are often multimodal and may include surgery as well as chemotherapy and/or radiation, which can cause considerable distress and anxiety related to loss of femininity or masculinity, concern over future fertility, or sexual dysfunction. Thus, tumors of the reproductive organs in pediatric/AYA patients require special consideration of the treatment effects beyond the intended oncologic outcome. Multidisciplinary teams should be involved in their care and address issues of fertility, sexual dysfunction, and psychosexual concerns before treatment begins. This review addresses histology, risk factors, prognosis, staging and treatment of gynecologic, breast and testicular cancers in pediatric and AYA patients.

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Ovarian tumors in children and adolescents: A series of 41 cases

Abstract: This semiological analysis confirms the role of imaging in diagnosing the etiology of ovarian lesions in children and adolescents and emphasizes the importance identifying tumoral hypervascularity, which, in addition to classic criteria, is highly predictive of malignancy.

Cited by 43 publications

References 32 publications

An intriguing case of precocious puberty due to an ovarian mass in an infant

An intriguing case of precocious puberty due to an ovarian mass in an infant

Ovarian tumors: General, surgical and oncological aspects

Pediatric, adolescent, and young adult breast and reproductive tumors

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