Ovarian Tumors

Templeman, Claire; Fallat, Mary E.

doi:10.1016/b978-0-323-02842-4.50039-5

Cited by 7 publications

(4 citation statements)

References 179 publications

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“…Over 70% of our patients had oophorectomy for their ovarian neoplasms. It has been estimated that the annual incidence of combined benign and malignant ovarian neoplasms is approximately 2.6 cases per 100 000 girls younger than 15 years 14 . The predominance of mature teratoma (52%) and 29% being malignant tumours in the present study were in agreement with previous reports 14–16 .…”

Section: Discussionsupporting

confidence: 93%

“…It has been estimated that the annual incidence of combined benign and malignant ovarian neoplasms is approximately 2.6 cases per 100 000 girls younger than 15 years 14 . The predominance of mature teratoma (52%) and 29% being malignant tumours in the present study were in agreement with previous reports 14–16 . We and others did not find that age was useful to distinguish patients having malignant neoplasms from the vast majority of others having benign conditions 1 .…”

Section: Discussionsupporting

confidence: 92%

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Oophorectomy in children. Who and why: 13‐year experience in a single centre

Wong

Tam

Pang

et al. 2012

J Paediatrics Child Health

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Section: Discussionsupporting

confidence: 93%

Section: Discussionsupporting

confidence: 92%

Oophorectomy in children. Who and why: 13‐year experience in a single centre

Wong

Tam

Pang

et al. 2012

J Paediatrics Child Health

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“…The sperm of men before treatment may have poor DNA integrity, although in 1 reported cohort of pediatric cancer survivors, DNA integrity of sperm seemed similar to age-matched controls. 74 Ovarian metastatic involvement has been seen in childhood tumors, such as neuroblastoma, Wilms' tumor, lymphoma, osteosarcoma, Ewing sarcoma, and extragenital rhabdomyosarcoma, 75 and in adult women with breast cancer. In a child or adolescent with 1 of these tumors, there is not a specific contraindication to ovarian-tissue cryopreservation if it is available, but the potential risk of development of a metastatic tumor in the reproductive tract must be considered and fully disclosed to the patient and family before proceeding.…”

Section: Ethical Issuesmentioning

confidence: 99%

Preservation of Fertility in Pediatric and Adolescent Patients With Cancer

Fallat¹,

Hutter²

2008

Pediatrics

Self Cite

225

103

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“…Androgen production by the tumor causes amenorrhea. 15 These small tumors may be found incidentally during excision of gonadic streaks or dysgenetic gonads. The tumors become invasive early, and gonadectomy is recommended as soon as 46XY gonadic dysgenesis is diagnosed.…”

Section: Discussionmentioning

confidence: 98%

Neonatal Gonadoblastoma

Bleve

Michelini

Cavazzini

et al. 2012

Journal of Gynecologic Surgery

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Background: Gonadoblastomas are very rarely found in children, considering that primary tumors of the ovaries are uncommon such patients. Case: This report describes a case of gonadoblastoma that was found and treated in a 4½-month-old girl. She had a cystic ovarian mass of 5-6 cm in diameter, which initially appeared as a follicular cyst without signs of being complicated. An operation was performed to access the mass. After this first operation, histopathology testing revealed the presence of a gonadoblastoma in the cyst wall while the patient's karyotype was and is 46 XX (normal female type). The patient then underwent a salpingo-oophorectomy to remove the tumor. Results: There were no dysgenetic gonads in this patient. Her prognosis was good. Conclusions: Gonadoblastoma is a rare tumor in children, occurring either in intersex disorders or in children with abnormal gonads. No data are published on the race distribution of this disease. These tumors are normally more frequent in phenotypic females who present with a genetic karyotype with an Y chromosome. In particular, 80% of gonadoblastomas occur in phenotypic females with intra-abdominal testis, while in the remaining 20% of these patients the tumors occur in patients who have other conditions involving intersexuality. For these reasons, this case was very anomalous and rare and, prior to this report, has never been described in literature. ( J GYNECOL SURG 28:165)

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Ovarian Tumors

Cited by 7 publications

References 179 publications

Oophorectomy in children. Who and why: 13‐year experience in a single centre

Oophorectomy in children. Who and why: 13‐year experience in a single centre

Preservation of Fertility in Pediatric and Adolescent Patients With Cancer

Neonatal Gonadoblastoma

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