Ovarian Steroid Cell Tumors, Not Otherwise Specified: A Case Report and Literature Review

Ovarian Steroid Cell Tumor Associated to Endometrial Hyperplasia and Presenting as Postmenopausal Vaginal Bleeding

“…Complete work-out for women with virilization includes bimanual exam, serum hormones and tumor markers, abdominal and endovaginal ultrasound and CT or MR of the adrenals and ovaries [17][18][19]. Endometrial sampling is mandatory in patients with postmenopausal bleeding or abnormal menses.…”

“…If genesic wishes are complete, hysterectomy, bilateral oophorectomy and complete surgical staging is recommended. Monitoring of hormone levels must be included in postoperative follow-up [3,19]. The paper of radiotherapy or chemotherapy is not well established.…”

“…Chemotherapy should be based on malignant factors in histology examination and stage of the tumor. Few studies are available, but BEP (bleomycin, etoposide and cisplatin) appears to be an active first-line chemotherapy regimen for malignant stromal tumors [19,25].…”

A Rare Case of Lipoid Cell Tumor of Ovary

“…It has been reported in 93-year-old lady with virilization 5 as well as in 8-year-old prepubertal girl with androgenic pseudoprecocity. 6 The major symptoms detected in 56 to 77% of patients are hirsutism and virilization. Reedy et al reported a case of an undifferentiated NOS steroid cell tumor with hirsutism, amenorrhea, clitoromegaly and temporal baldness.…”

Virilisation due to an ovarian steroid cell tumour in a child with Turner syndrome

“…Steroid cell tumours are rare in children 3 . These tumours commonly secrete testosterone 4 but are known to cause isosexual or heterosexual precocious pseudopuberty 3,4,5 and are thought to be benign when they occur in prepubertal children 3 .…”