Ovarian sex cord tumor with annular tubules associated with precocious puberty

Non-Peutz-Jeghers syndrome associated ovarian sex cord tumor with annular tubules: a case report

“…Sex cord tumor with annular tubules (SCTAT) is a rare ovarian neoplasm that accounts for 6% of sex cord stromal tumors, which may in turn account for only approximately 5% of all ovarian neoplasms (1,2). It was first described in 1970 by Scully (3), who characterized the tumor's unique histopathology consistent with coexistence of simple and complex annular tubules.…”

“…The majority of patients with SCTAT are of reproductive age (5); therefore, our case is rare, a young girl with SCTAT who presented with precocious puberty as determined by breast budding, pubic hair growth, and vaginal bleeding. A limited number of such pediatric cases have been described in the U.S. literature (2,(6)(7)(8)(9)(10)(11)(12).…”

Retroperitoneal Recurrence in Ovarian Sex Cord Stromal Tumor with Annular Tubules 16 Years Later.

“…These malignancies are typically diagnosed at an apparently early stage and generally have a favorable prognosis. Sex cord tumor with annular tubules (SCTAT) is a rare ovarian neoplasm that accounts for 6% of sex cord stromal tumors [4,5]. The predominant component of this tumor has intermediate morphologic features between granulosa cell tumors and Sertoli cell tumors and focal differentiation into either of these tumor types may occur [7].…”

“…Sex cord tumor with annular tubules (SCTAT) is a rare ovarian neoplasm that accounts for 6% of sex cord stromal tumors [4,5]. It was first described in 1970 by Scully, who characterized the tumor's unique histopathology consistent with coexistence of simple and complex annular tubules [6].…”

Causa muy rara de pubertad precoz periférica en una niña: tumor de cordones sexuales con túbulos anulares

“…1,6,7 En raras ocasiones, se presentan en la primera década de la vida, etapa en la que suele diagnosticarse por la aparición de una pubertad precoz isosexual. 2,3,[7][8][9] Ello se debe a que son tumores productores de hormonas, fundamentalmente, estrógenos y progesterona. 10 Dada la rareza de estos tumores, en general, y en la edad pediátrica, en particular, comunicar un nuevo caso, en una niña de 6 años, puede ser de utilidad para conocer mejor esta entidad.…”