2022
DOI: 10.1262/jrd.2021-119
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Ovarian response to prostaglandin F<sub>2α</sub> in lactating dairy cows: A clinical update

Abstract: Prostaglandin F2α (PGF2α) and its analogs are used to induce luteolysis in estrus synchronization programs to terminate unwanted pregnancies or to promote ovulation in certain cow subpopulations. In the past few decades, the luteolytic dose of PGF2α has remained unchanged. This review explores the clinical implications of increasing the standard dose for these applications in high-producing dairy cows. Ultrasonography may assist in selecting the most appropriate PGF2α dose and improve the results. A reference … Show more

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Cited by 2 publications
(2 citation statements)
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References 98 publications
(144 reference statements)
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“…A separate study (Hatler et al, 2003) noted that 66 % of ovarian cysts in dairy cattle were associated with suprobal levels of progesterone, which blocks preovulatory elevated luteinizing hormone levels but does not suppress pulsatility as it occurs with average luteal progesterone concentrations. That is, an anovulatory persistent follicle begins to develop with a larger diameter and longer duration of existence than usual, along with an increase in peripheral estradiol concentrations (López-Gatius, 2022).…”
Section: Postpartum Complications In Cows Are Associated With Hormona...mentioning
confidence: 99%
“…A separate study (Hatler et al, 2003) noted that 66 % of ovarian cysts in dairy cattle were associated with suprobal levels of progesterone, which blocks preovulatory elevated luteinizing hormone levels but does not suppress pulsatility as it occurs with average luteal progesterone concentrations. That is, an anovulatory persistent follicle begins to develop with a larger diameter and longer duration of existence than usual, along with an increase in peripheral estradiol concentrations (López-Gatius, 2022).…”
Section: Postpartum Complications In Cows Are Associated With Hormona...mentioning
confidence: 99%
“…The risk of the ageing of gametes, particularly the postovulatory oocyte, becomes critical at the time of AI in cattle [ 28 , 29 , 30 ]. Owing to the challenges of correctly detecting estrus, hormonal protocols for fixed-time AI (FTAI) have been incorporated into routine intensive dairy farming reproductive management programs [ 31 , 32 , 33 , 34 ]. However, most Ais worldwide are performed at spontaneous estrus and hormone treatments have met with strong consumer opposition in some countries.…”
Section: Introductionmentioning
confidence: 99%