Ovarian Response to Gonadotropins in Patients With Tubal Factor Infertility: Salpingectomy Versus Nonsalpingectomy

Lin, Yu‐Jen; Ou, Yu‐Che; Huang, Fu-Jen; Lin, Pin‐Yao; Kung, Fu‐Tsai; Lan, Kuo‐Chung

doi:10.1016/j.jmig.2013.04.005

Cited by 18 publications

(20 citation statements)

References 13 publications

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“…The principal indication for the surgery was a previous ectopic pregnancy/ies and hydrosalpinx in 7 [1, 5, 12, 20, 27, 29, 30] and 13 studies [2–4, 6–11, 17, 18, 21, 25], respectively. In 4 studies, both patients treated for ectopic pregnancy and hydrosalpinx were included in the analysis [19, 22, 24, 28]. …”

Section: Resultsmentioning

confidence: 99%

“…Plasmatic E 2 levels on the day of human chorionic gonadotropin (hCG) administration (for ovulation triggering) resulted nonsignificant different between salpingectomy and non-salpingectomy arms in 10 studies [1, 2, 8, 12, 17–20, 24, 28]. In only one retrospective analysis, including 40 patients treated by salpingectomy due to hydrosalpinx compared to 103 patients with tubal factor infertility (no hydrosalpinx), reported a significant reduction in E 2 levels in the salpingectomy group [10].…”

Section: Resultsmentioning

confidence: 99%

“…A total of 21 studies described the absence of any significant difference in terms of number of oocytes retrieved between salpingectomy and non-salpingectomy patients or in pre and post-surgical procedure in the same cohort of women [2–4, 6–12, 17–22, 24, 27, 28, 30]. Lass et al [1] compared 29 patients treated by salpingectomy for ectopic pregnancy to 73 healthy women reporting a significant reduction in oocyte yield in the ipsilateral compared to the contralateral ovary.…”

Section: Resultsmentioning

confidence: 99%

“…All 11 [2, 4, 6, 7, 9–12, 20, 22, 28] and 14 [1, 3–5, 7–9, 11, 18, 22, 24, 25, 29, 30] studies which analyzed, respectively, the number of embryos obtained and of embryos transferred found no statistically significant difference between salpingectomy and non-salpingectomy patients.…”

Section: Resultsmentioning

confidence: 99%

“…One RCT and one retrospective study found no significant differences between treated and untreated women, even if surgically treated patients for hydrosalpinx showed a better implantation rate in terms of absolute value compared to untreated subjects [2, 10]. Two further retrospective studies found no significant improvement of implantation rate in patients after salpingectomy; however, in these cases, the control subjects were represented by patients with tubal factor infertility without hydrosalpinx [3, 24]. …”

Section: Resultsmentioning

confidence: 99%

See 4 more Smart Citations

Salpingectomy before assisted reproductive technologies: a systematic literature review

et al. 2016

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Salpingectomy is largely used in case of hydrosalpinx in infertile women scheduled for assisted reproductive technologies (ART), whereas there is no consensus on its role in absence of hydrosalpinx. The current is a systematic literature review to collate all available evidence regarding salpingectomy as fertility enhancement procedure before ART in infertile patients. Our primary endpoint was to assess the impact of the surgical procedure on ovarian reserve, and secondary outcomes were to evaluate its benefits and harms on ART outcomes. We identified 29 papers of which 16 reporting data on the impact of tubal surgery on ovarian reserve and 24 (11 previously included) on ART outcomes. Available data suggested an absence of variation in ovarian reserve markers after unilateral salpingectomy while contradictory results were reported for bilateral surgery. Considering ART outcomes, data reported a significant improvement in ongoing pregnancy/live-birth rate in treated subjects without significant reduction in ovarian response to gonadotropin stimulation. In case of tubal disease, a surgical approach based on unilateral salpingectomy may be considered safe, without negative effects on ovarian reserve and ovarian response to controlled ovarian stimulation whilst having a positive effect on pregnancy rate. Data regarding bilateral salpingectomy and ovarian reserve are conflicting. Further trials are needed to confirm both the benefits of salpingectomy before ART and the safety of bilateral salpingectomy on ovarian reserve, and to clarify the role of uni- or bilateral surgery in case of tubal blockage without hydrosalpinx.

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Section: Resultsmentioning

confidence: 99%

Section: Resultsmentioning

confidence: 99%

Section: Resultsmentioning

confidence: 99%

Section: Resultsmentioning

confidence: 99%

Section: Resultsmentioning

confidence: 99%

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Salpingectomy before assisted reproductive technologies: a systematic literature review

et al. 2016

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Fallopian Tube Ligation or Salpingectomy as Means for Reducing Risk of Ovarian Cancer

Szender

Lele²

2015

AMA Journal of Ethics

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The Problem of Ovarian Cancer Ovarian cancer remains the most lethal gynecologic malignancy in the United States, both in rate of fatality (64 percent of patients ultimately die of their disease [1]) and in overall deaths (14,270 in 2014 [2]). Although 50-75 percent of patients treated with chemotherapy initially respond to the medications, most will have recurrences of the disease [1]. The driving force behind the poor survival rates is the stage at diagnosis. Approximately 65 percent of patients present with widespread (stages III or IV) disease, at which point cure is uncommon [2]. For patients with stage I disease, on the other hand, five-year survival rates exceed 90 percent [2].

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High miscarriage rate in women treated with Essure® for hydrosalpinx before embryo transfer: a systematic review and meta‐analysis

Barbosa

Sotiriadis

Papatheodorou

et al. 2016

Ultrasound in Obstet & Gyne

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The available evidence suggests that, although Essure prior to ET in women with hydrosalpinx improves the chance of achieving a clinical pregnancy compared with no intervention, it is associated with a higher rate of miscarriage when compared with the other interventions. Although this evidence is based on observational studies, we believe that salpingectomy should be the first option for women who are eligible for videolaparoscopy. However, it is still premature to make recommendations for women who are not eligible for surgery, and randomized controlled trials are needed to clarify which is the best treatment alternative in such a scenario. Copyright © 2016 ISUOG. Published by John Wiley & Sons Ltd.

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Ovarian Response to Gonadotropins in Patients With Tubal Factor Infertility: Salpingectomy Versus Nonsalpingectomy

Cited by 18 publications

References 13 publications

Salpingectomy before assisted reproductive technologies: a systematic literature review

Salpingectomy before assisted reproductive technologies: a systematic literature review

Fallopian Tube Ligation or Salpingectomy as Means for Reducing Risk of Ovarian Cancer

High miscarriage rate in women treated with Essure® for hydrosalpinx before embryo transfer: a systematic review and meta‐analysis

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