Ovarian recurrence from a Stage 1b1 cervical adenocarcinoma previously treated with radical vaginal trachelectomy: A case report

Brockbank, Elly; Evans, Joanne; Singh, Naveena; Shepherd, John H.; Jeyarajah, Arjun

doi:10.1016/j.gynor.2012.01.001

Cited by 5 publications

(6 citation statements)

References 10 publications

(10 reference statements)

Supporting

Mentioning

Contrasting

Order By: Relevance

“…The temporal relationship between the primary cervical and secondary ovarian tumours is of interest. In the largest single series of such cases ( n = 29), clinically detectable ovarian disease was seen to precede, coincide with or (in the most clinically confounding of them) occur some years after the index cervical cancer, indicating their inherent latency . In 17 of 29 cases with documented follow‐up (ranging from 4 to 83 months), the diagnosis was of HPVA EAC.…”

Section: Cervical Adenocarcinomas With Ovarian Metastases Simulating mentioning

confidence: 97%

“…In the largest single series of such cases (n = 29), clinically detectable ovarian disease was seen to precede, coincide with or (in the most clinically confounding of them) occur some years after the index cervical cancer, indicating their inherent latency. 57,58,110 In 17 of 29 cases with documented follow-up (ranging from 4 to 83 months), the diagnosis was of HPVA EAC. Twelve of 17 cases had an isolated ovarian secondary, and 5 of 17 had extraovarian disease.…”

Section: Cervical Adenocarcinomas With Ovarian Metastases Simulating mentioning

confidence: 99%

See 1 more Smart Citation

Metastases to the ovary arising from endometrial, cervical and fallopian tube cancer: recent advances

Casey

Singh

2019

Histopathology

View full text Add to dashboard Cite

The introduction of genomic studies has enabled assessment of the clonality of synchronous tumours involving the ovary and other sites in the female genital tract in a definitive way. This has led to the abandonment of conventional approaches to primary site assignment, and the recognition that most such synchronous neoplasms are clonally related single tumours with metastatic spread, rather than independent primary tumours. These discoveries have implications for diagnostic practice, analogous to the gradual change over the last few decades in our approach to mucinous neoplasms of the ovary metastatic from the gastrointestinal tract. In this review, we first examine the routes of metastasis to the ovary, and then discuss the diagnostic and clinical implications of concurrent ovarian carcinomas arising in combination with endometrial, endocervical and tubal carcinomas. It is proposed that cases of primary low‐grade endometrioid endometrial carcinoma with a secondary unilateral ovarian tumour, both with indolent characteristics, may be classified as ‘FIGO stage IIIA‐simulating independent primary tumours’, with a comment that conservative management would be appropriate. It should be recognised that human papillomavirus‐associated endocervical adenocarcinomas may result in synchronous or metachronous ovarian metastases that appear to be unrelated to the primary tumour, and that these may be managed conservatively in the absence of other sites of disease. In cases of tubo‐ovarian high‐grade serous carcinoma, tubal intraepithelial or contralateral adnexal involvement should count as a pelvic disease site for staging purposes.

show abstract

Section: Cervical Adenocarcinomas With Ovarian Metastases Simulating mentioning

confidence: 97%

Section: Cervical Adenocarcinomas With Ovarian Metastases Simulating mentioning

confidence: 99%

Metastases to the ovary arising from endometrial, cervical and fallopian tube cancer: recent advances

Casey

Singh

2019

Histopathology

View full text Add to dashboard Cite

show abstract

“…One important consideration that should be taken into account in the future study is the involvement of remnant or transposed ovaries in recurrence and metastasis after radical hysterectomy. Ovarian metastasis of cervical cancer has been documented in the literature, although the effect of histologic type is uncertain 30,31,32. In a large cohort of radical hysterectomy series, there was a significantly higher ovarian metastasis from adenocarcinoma (3.72%) than squamous cell types (0.22%) in stage IB cervical carcinoma 31.…”

Section: Discussionmentioning

confidence: 97%

“…Ovarian metastasis of cervical cancer has been documented in the literature, although the effect of histologic type is uncertain. 30 , 31 , 32 In a large cohort of radical hysterectomy series, there was a significantly higher ovarian metastasis from adenocarcinoma (3.72%) than squamous cell types (0.22%) in stage IB cervical carcinoma. 31 In our cohort, 56 patients (54.9%) were premenopausal, and 17 patients (30.3%) among them, underwent bilateral salpingo-oophorectomy, and only 8 patients received ovarian transposition.…”

Section: Discussionmentioning

confidence: 99%

Surgical Outcomes of Robotic Radical Hysterectomy Using Three Robotic Arms versus Conventional Multiport Laparoscopy in Patients with Cervical Cancer

et al. 2014

View full text Add to dashboard Cite

PurposeTo compare surgical outcomes of robotic radical hysterectomy (RRH) using 3 robotic arms with those of conventional laparoscopy in patients with early cervical cancer.Materials and MethodsA retrospective cohort study included 102 patients with stage 1A1-IIA2 cervical carcinoma, of whom 60 underwent robotic and 42 underwent laparoscopic radical hysterectomy (LRH) with pelvic lymph node dissection performed between December 2009 and May 2013. Perioperative outcomes were compared between two surgical groups.ResultsRobotic approach consisted of 3 robotic arms including the camera arm and 1 conventional assistant port. Laparoscopic approach consisted of four trocar insertions with conventional instruments. There were no conversions to laparotomy. Mean age, body mass index, tumor size, cell type, and clinical stage were not significantly different between two cohorts. RRH showed favorable outcomes over LRH in terms of estimated blood loss (100 mL vs. 145 mL, p=0.037), early postoperative complication rates (16.7% vs. 30.9%, p=0.028), and postoperative complications necessitating intervention by Clavien-Dindo classification. Total operative time (200.5±61.1 minutes vs. 215.6±83.1 minutes, p=0.319), mean number of lymph node yield (23.3±9.3 vs. 21.7±9.8, p=0.248), and median length of postoperative hospital stay (11 days vs. 10 days, p=0.129) were comparable between robotic and laparoscopic group, respectively. The median follow-up time was 44 months with 2 recurrences in the robotic and 3 in the laparoscopic cohort.ConclusionSurgical outcomes of RRH and pelvic lymphadenectomy were comparable to that of laparoscopic approach, with significantly less blood loss and early postoperative complications.

show abstract

“…In 2012, Brockbank et al 13 published a case of a 32 - year - old woman diagnosed with a stage IB1 grade II mucinous adenocarcinoma of the cervix, 1.5 cm in diameter, without nodal involvement o n MRI. She underwent a radical vaginal trachelectomy and pelvic lymphadenectomy.…”

Section: Discussant: Closing Summarymentioning

confidence: 99%

Ovarian metastasis after laparoscopic radical trachelectomy

Noll

Saadi

Wernicke

et al. 2019

Int J Gynecol Cancer

View full text Add to dashboard Cite

Ovarian recurrence from a Stage 1b1 cervical adenocarcinoma previously treated with radical vaginal trachelectomy: A case report

Abstract: ► Post cervical cancer treatment new pelvic abnormality must be regarded as recurrence. ► Benign MRI features does not exclude recurrence from previous cervical adenocarcinoma.

Cited by 5 publications

References 10 publications

Metastases to the ovary arising from endometrial, cervical and fallopian tube cancer: recent advances

Metastases to the ovary arising from endometrial, cervical and fallopian tube cancer: recent advances

Surgical Outcomes of Robotic Radical Hysterectomy Using Three Robotic Arms versus Conventional Multiport Laparoscopy in Patients with Cervical Cancer

Ovarian metastasis after laparoscopic radical trachelectomy

Contact Info

Product

Resources

About