Ovarian leukemia detected by pelvic sonography. A case report

Abstract

Asymmetric enlargement of the right adnexa in a prepubertal, asymptomatic, 7-year-old girl with acute lymphocytic leukemia (ALL) was detected by pelvic sonography as part of examinations after the discontinuation of therapy. The case is the first where asymptomatic ovarian relapse has been detected prospectively by sonography. The technique should be considered for the follow-up female patients with ALL in remission, although more extensive studies are needed to establish its effectiveness.

Unusual ovarian leukemic relapse in a girl with history of B‐cell lymphoblastic leukemia

“…Its diagnostic yield is low, given rarity of ovarian recurrence. However, it would be particularly useful in symptomatic patients 1,7 . In patients with a background of leukemia presenting with an ovarian mass, a higher level of suspicion is needed.…”

“…However, it would be particularly useful in symptomatic patients. 1,7 In patients with a background of leukemia presenting with an ovarian mass, a higher level of suspicion is needed. In the absence of evidence of bone marrow relapse at the conventional site, repeat marrow aspirate at another site would be warranted, as this affects the choice of management.…”

Unusual ovarian leukemic relapse in a girl with history of B cell lymphoblastic leukemia

“…Routine surveillance pelvic sonography is recommended for timely detection of pelvic extramedullary relapse. [7] In patients with background of leukaemia presenting with an ovarian mass, a higher level of suspicion needs to be kept. In the absence of evidence in bone marrow relapse at conventional site, repeat marrow aspirate at another site would be warranted since this affect the choice of management.…”