Ovarian gynandroblastoma with juvenile granulosa cell component and raised alpha fetoprotein

Chan, Renee C.F.; Tucker, Malcolm; Russell, Peter

doi:10.1080/00313020500169503

Cited by 13 publications

(9 citation statements)

References 8 publications

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“…Approximately 97% of JGCTs occur during the first three decades of life. Only a few known cases of JGCT occurred in women > 30 years old; just two cases of JGCT as a component of gynandroblastoma have been reported in patients over the age of 30 [ 2 , 7 ]. Thus, our case of gynandroblastoma with JGCT in a postmenopausal woman is extremely unusual.…”

Section: Discussionmentioning

confidence: 99%

Ovarian Gynandroblastoma with a Juvenile Granulosa Cell Tumor Component in a Postmenopausal Woman: A Case Report and Literature Review

Jang

Lee

Jang

et al. 2018

J Pathol Transl Med

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Gynandroblastoma is an extremely rare sex cord-stromal tumor with both female (granulosa cell tumor) and male (Sertoli-Leydig cell tumor) elements. Juvenile granulosa cell tumors are also very rare and are so named because they usually occur in children and adolescents. A 71-year-old woman with right upper quadrant abdominal pain visited our hospital. Pelvic computed tomography showed a large multilocular cystic mass, suspected to be of ovarian origin. We performed a total abdominal hysterectomy (total abdominal hysterectomy was performed) with bilateral salpingo-oophorectomy. A 13-cm multilocular cystic mass with serous fluid was observed in her right ovary. Upon microscopic examination, the solid component of the mass showed both Sertoli-Leydig cell and juvenile granulosa cell differentiation, which we diagnosed as gynandroblastoma. Gynandroblastoma with a juvenile granulosa cell tumor component is extremely rare and, until now, only six cases have been reported in the English literature. We report the first gynandroblastoma with a juvenile granulosa cell tumor component diagnosed in an elderly patient, along with a literature review.

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Section: Discussionmentioning

confidence: 99%

Ovarian Gynandroblastoma with a Juvenile Granulosa Cell Tumor Component in a Postmenopausal Woman: A Case Report and Literature Review

Jang

Lee

Jang

et al. 2018

J Pathol Transl Med

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“…Notre cas serait le 39 e cas rapporté dans la littérature depuis 1930, selon la base de données Pubmed [4][5][6].…”

Section: Discussionunclassified

Gynandroblastome et syndrome de l’X Fragile. À propos d’un cas

Lejeune

Gallon

Quirin³

et al. 2011

Gynécologie Obstétrique & Fertilité

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“…Les publications de gynandroblastomes sont rares. Vingt-quatre cas sont rapportés jusqu'en 1967 [3], neuf cas de 1967 à 1994 [11], puis trois cas jusqu'en 2005 [12], soit un total de 36 cas dans le monde. Notre cas serait le 37 e .…”

Section: Discussionunclassified

“…Dans notre cas, l'analyse de l'utérus retrouvait également une hyperplasie de l'endomètre. L'α-foetoprotéine peut être élevée [12].…”

Section: Discussionunclassified

Gynandroblastome: une tumeur rare de l'ovaire. À propos d'un cas

Kapella¹,

Bakeland²,

Blin³

et al. 2007

Gynécologie Obstétrique & Fertilité

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Ovarian gynandroblastoma with juvenile granulosa cell component and raised alpha fetoprotein

Cited by 13 publications

References 8 publications

Ovarian Gynandroblastoma with a Juvenile Granulosa Cell Tumor Component in a Postmenopausal Woman: A Case Report and Literature Review

Ovarian Gynandroblastoma with a Juvenile Granulosa Cell Tumor Component in a Postmenopausal Woman: A Case Report and Literature Review

Gynandroblastome et syndrome de l’X Fragile. À propos d’un cas

Gynandroblastome: une tumeur rare de l'ovaire. À propos d'un cas

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