Ovarian granulosa cell tumours adherent to other abdominal organs; surgical removal from 2 Warmblood mares

Summary Granulosa cell tumour (GCT) is reported to be the most common ovarian neoplasm in the mare. A multicentre retrospective study evaluating the medical records of horses undergoing ovariectomy for treatment of a GCT was undertaken, documenting the presenting clinicopathological features, treatment and outcome. Follow‐up information was obtained by telephone questionnaire. Fifty‐two mares were included. Most presented with behavioural/reproductive abnormalities, including stallion‐like behaviour (50%), aggression (31%), prolonged oestrus or nymphomania (19%), and persistent anoestrus (8%). Most (93%) affected ovaries had a multilocular appearance when examined ultrasonographically. Only 60% of horses with histopathologically confirmed GCTs demonstrated elevations in serum inhibin concentrations. Twenty‐five percent of horses had histopathologically confirmed bilateral GCTs. Ninety‐four percent of horses that underwent ovariectomy were discharged from the hospital. Standing laparoscopic ovariectomies had a lower complication rate (34%) than other surgical methods. Long‐term complications were uncommon (11%). In conclusion, histopathologically confirmed GCTs can occur in the presence of normal serum inhibin concentrations. The high prevalence of bilateral GCTs indicates that thorough evaluation of the contralateral ovary is necessary. Surgical ovariectomy for treatment of GCTs has favourable short‐ and long‐term outcomes. Standing laparoscopic ovariectomy may be associated with a lower complication rate than other surgical methods.

“…), adhesions between the tumours and other intra‐abdominal organs (Rambags et al . ), weight loss (Nyack and Johnson ; McCue ) and lameness (Meagher et al . ).…”

Section: Discussionmentioning

confidence: 99%

Granulosa cell tumours in the mare: A review of 52 cases

Sherlock

Lott-Ellis

Bergren

et al. 2015

“…Granulosa thecal cell (GTC) tumours are the most common form of ovarian neoplasia in the mare (Hughes et al . 1980; Rambags et al . 2003; Ellenberger et al .…”

Section: Introductionmentioning

confidence: 99%

Granulosa thecal cell tumour in a mare causing hypertrophic osteopathy

Packer

McKANE²

2011

Summary Hypertrophic osteopathy (HO) is a rare condition in the horse characterised by symmetrical proliferation of connective tissue and subperiosteal bone, along the diaphyses of limb bones. In this case, a 10‐year‐old Irish Draught cross Thoroughbred mare was presented for investigation of weight loss, lethargy and firm swelling of all 4 distal limbs. Radiographs of the distal limbs revealed palisade‐like periosteal new bone formation perpendicular to the cortex of the distal third metacarpal and metatarsal bones, proximal (P1) and mid (P2) phalanges. Rectal examination revealed a mass of approximately 20 x 30 cm in the right caudoventral abdomen. The mare was diagnosed with HO due to a granulosa thecal cell (GTC) tumour. The GTC tumour was removed and the diagnosis confirmed on histological examination. Clinical examination and radiographs of the distal limbs after surgery demonstrated reduction in size of the limb swellings and new bone formation. To the authors' knowledge this is the first report of HO due to a GTC tumour in a mare.

“…2005; De Backer et al . 2005), and has also been described in 2 Warmblood mares suffering from ovarian granulosa cell tumours (Rambags et al . 2003).…”

Section: Discussionmentioning

confidence: 78%

An abdominal teratoma in a yearling Irish Cob with a strangulating obstruction of the small intestine

Arensburg¹,

Olivier

Boussauw

et al. 2011

Summary A yearling Irish Cob stallion was presented to De Morette Equine clinic for severe acute abdominal pain, nonresponsive to analgesics and sedatives. Rectal palpation and a limited transabdominal ultrasonographic examination led to the presumptive diagnosis of a strangulated obstruction of the small intestine. The painful behaviour of the pony did not allow conservative treatment and surgical exploration was denied by the owners for financial considerations. On necropsy, a large cystic mature teratoma was adhered to the ventral body wall, the mesenteric root, omentum and intestines. Teratomas are rare in man and animals, and an extragonadal intraperitoneal location has not previously been reported in the equine species.