Ovarian Factors of Cardiovascular Disease: The Way to Go?

Abstract

The function of the female reproductive system is critically dependent on the general health of a woman. However, the activity of ovaries has its projection on metabolic processes, vascular tone, and endothelial function. Hyperandrogenicity in polycystic ovarian disease is a trigger for adiposity, diabetes type II, and atherogenic vasculopathy. The increased level of testosterone persists to stay even after menopause. The data on hormonal changes during menopause is discussed. Hormone replacement therapy did not demonstrate an evident beneficial effect on the cardiovascular system. The possible therapeutic strategy for improved cardiovascular health during the transitional year of life is presented. The use of diet, L-arginine, and xylitol could be a reasonable option in the management of perimenopausal women.