Ovarian cancer: density equalizing mapping of the global research architecture

Brüggmann, Dörthe; Pulch, Katharina; Klingelhöfer, Doris; Pearce, Celeste Leigh; Groneberg, David A.

doi:10.1186/s12942-016-0076-2

Cited by 31 publications

(34 citation statements)

References 55 publications

(56 reference statements)

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“…Furthermore, most of the social networking sites were established and founded in the USA. These findings are similar to those found in previous bibliometric studies in different fields, principally that the USA had the highest activity in scientific research output worldwide and in international collaboration networks, as well as the highest h-index [32,[35][36][37]. Regarding the international collaboration, this emphasizes the significance of global networking and its impact on research output [38][39][40][41].…”

Section: Resultssupporting

confidence: 90%

Global trends in research related to social media in psychology: mapping and bibliometric analysis

Zyoud

Sweileh

Awang

et al. 2018

Int J Ment Health Syst

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BackgroundSocial media, defined as interactive Web applications, have been on the rise globally, particularly among adults. The objective of this study was to investigate the trend of the literature related to the most used social network worldwide (i.e. Facebook, Twitter, LinkedIn, Snapchat, and Instagram) in the field of psychology. Specifically, this study will assess the growth in publications, citation analysis, international collaboration, author productivity, emerging topics and the mapping of frequent terms in publications pertaining to social media in the field of psychology.MethodsPublications related to social media in the field of psychology published between 2004 and 2014 were obtained from the Web of Science. The records extracted were analysed for bibliometric characteristics such as the growth in publications, citation analysis, international collaboration, emerging topics and the mapping of frequent terms in publications pertaining to social media in the field of psychology. VOSviewer v.1.6.5 was used to construct scientific maps.ResultsOverall, 959 publications were retrieved during the period between 2004 and 2015. The number of research publications in social media in the field of psychology showed a steady upward growth. Publications from the USA accounted for 57.14% of the total publications and the highest h-index (48).The most common document type was research articles (873; 91.03%). Over 99.06% of the publications were published in English. Computers in Human Behavior was the most prolific journal. The University of Wisconsin–Madison ranked first in terms of the total publications (n = 39). A visualisation analysis showed that personality psychology, experimental psychology, psychological risk factors, and developmental psychology were continual concerns of the research.ConclusionsThis is the first study reporting the global trends in the research related to social media in the psychology field. Based on the raw data from the Web of Science, publication characteristics such as quality and quantity were assessed using bibliometric techniques over 12 years. The USA and its institutions play a dominant role in this topic. The most preferred topics related to social media in psychology are personality psychology, experimental psychology, psychological risk factors, and developmental psychology.

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Section: Resultssupporting

confidence: 90%

Global trends in research related to social media in psychology: mapping and bibliometric analysis

Zyoud

Sweileh

Awang

et al. 2018

Int J Ment Health Syst

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“…Ovarian cancer (OC) is the most common malignancy in women, and its incidence is increasing worldwide [1]. Despite the development of surgery and adjuvant therapies, the overall prognosis of patients with OC remains poor, especially in those with advanced stage disease [2].…”

Section: Introductionmentioning

confidence: 99%

PRR11 Overexpression Facilitates Ovarian Carcinoma Cell Proliferation, Migration, and Invasion Through Activation of the PI3K/AKT/β-Catenin Pathway

Zhu

Wang

et al. 2018

Cell Physiol Biochem

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Background/Aims: Ovarian cancer (OC) is the most lethal gynecologic malignancy, mainly due to the advanced stage at diagnosis in most patients and high rate of relapse. Thus, it is still essential to elucidate the underlying mechanisms and explore the diagnostic and therapeutic targets of OC. Recent studies have revealed that proline-rich protein 11 (PRR11) is dysregulated in different cancers, participating in their initiation and progression; however, it remains unclear whether PRR11 is involved in OC. Methods: Immunohistochemical staining, quantitative reverse transcription PCR, and western blotting were performed to evaluate PRR11 expression in OC tissues and cells. The relationship between PRR11 expression and the clinicopathologic data of patients were analyzed. We upregulated and downregulated PRR11 expression using a PRR11 overexpression vector and PRR11-specifc small interfering RNA, respectively, to further clarify its role in the malignant biological behavior of OC in vitro. Results: Overexpression of PRR11 in OC tissues and cells significantly correlated with advanced FIGO stage, lymph node metastasis, and large tumor size. Downregulation of PRR11 inhibited cell proliferation and prevented the invasion and migration of HO-8910 OC cells, whereas opposite results were observed in Caov3 cells upon PRR11 upregulation. Further analyses showed that PRR11 positively regulated cell proliferation-related proteins, including c-myc and cyclin D1, and increased and decreased the expression of matrix metalloproteinase 2 and tissue inhibitor of metalloproteinase 2, respectively. Additionally, our preliminary results demonstrated that PRR11 expression was mediated by the phosphoinositide 3-kinase/AKT/β-catenin signaling pathway. Conclusion: The results of this study provide evidence that PRR11 plays a critical role in the progression and metastasis of OC, and as such, may serve as a potential prognostic and therapeutic target in OC.

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“…China-a rising star in many areas of science-does also appear in some NewQIS assessments prominently as shown for ovarian cancer research in Fig. 3c (Bruggmann et al 2017d). Concerning Asian countries, a previous assessment of 5527,558 articles has indicated that Asian countries have largely different research focuses in comparison to Western countries (Groneberg-Kloft et al 2008b).…”

Section: Visualizationmentioning

confidence: 84%

“…c DEMP exemplifying prominent Chinese research activities in ovarian cancer research. Data fromBruggmann et al (2017d)…”

mentioning

confidence: 99%

New quality and quantity indices in science (NewQIS): results of the first decade—project progress review

et al. 2019

Self Cite

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Strategies employing information science and scientometric approaches were introduced to science policy and management over the past decades. As a rapidly evolving field, new bibliometric parameters are proposed and discussed continuously and the fields also benefits from the introduction of novel visualization techniques. The present article summarizes the experiences with a platform that combines geographical mapping with scientometrics. It was established between 2005 and 2008 at the Charité in Berlin and termed "New Quality and Quantity Indices in Science" (NewQIS), consisting of the integration of common scientometric parameters such as the h-index and novel visualization techniques including density equalizing mapping. NewQIS was used to assess socio-economic important fields of medicine and sciences. Within NewQIS studies, research activities, citation patterns and their relation to socio-economic figures were analyzed with regard to time periods, countries, continents or even single cities. Within the decade after its establishment, more than 80 NewQIS articles were peer-reviewed and published. Being a non-funded low budget project, it was used by many medical students to conduct their MD thesis. The narrow technical frame led to the chance of a comparison of research output between different fields of science. This article summarizes NewQIS 1.0 activities, discusses its limits and gives a look into the future of NewQIS 2.0 with a target of 200 evaluated entities of the biomedical field of sciences.

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Ovarian cancer: density equalizing mapping of the global research architecture

Cited by 31 publications

References 55 publications

Global trends in research related to social media in psychology: mapping and bibliometric analysis

Global trends in research related to social media in psychology: mapping and bibliometric analysis

PRR11 Overexpression Facilitates Ovarian Carcinoma Cell Proliferation, Migration, and Invasion Through Activation of the PI3K/AKT/β-Catenin Pathway

New quality and quantity indices in science (NewQIS): results of the first decade—project progress review

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