Ovarian Cancer Complicating Pregnancy

Boulay, Richard; Podczaski, Edward S.

doi:10.1016/s0889-8545(05)70012-7

Cited by 125 publications

(42 citation statements)

References 39 publications

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“…The majority of these tumors consists of germ-cell tumors and borderline tumors (table 2). A recent review of the literature reveals about 30 cases of Krukenberg tumors in pregnant women [29]. Mostly, this type of tumor originated from gastric carcinoma, followed in frequency by metastasis from cancer of the large intestine, appendix, and breast.…”

Section: Histological Characteristics Of Ovarian Masses Diagnosed Andmentioning

confidence: 99%

Adnexal Masses in Pregnancy

et al. 2003

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With the widespread use of routine abdominal ultrasound examination during pregnancy, adnexal masses are observed with increasing frequency. Most patients are clinically asymptomatic at the time of presentation, and most of the adnexal masses detected during early pregnancy disappear during the first 16 weeks of pregnancy. Ovarian tumors are estimated to occur in about 1 in 1,000 pregnancies and of these 3% are malignant. Here we present an overview about frequency, diagnostic procedures and pathological characteristics of these ovarian tumors. Moreover, current modalities for treatment during pregnancy are summarized. Surgical treatment of the adnexal masses has to be performed with adequate staging and debulking equal to the treatment of non-pregnant women. However, whereas during organogenesis abortion has to be considered prior to chemotherapy, later in pregnancy surgical debulking as complete as possible, followed by taxol-platinum chemotherapy is indicated. If the fetus is not viable at the time of primary surgery, neoadjuvant chemotherapy and complementation of surgery after delivery of the baby should be performed. It should be stressed that chemotherapy for ovarian cancer applied during pregnancy appears to be safe. However, no studies have evaluated the long-term consequences for children exposed to intra-uterine chemotherapy. Aspiration of cysts should be avoided, as the correlation between the histological evaluation of an ovarian malignancy and the cytological evaluation of aspirates is poor. Moreover, spillage of malignant cysts is hazardous for the patient.

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Section: Histological Characteristics Of Ovarian Masses Diagnosed Andmentioning

confidence: 99%

Adnexal Masses in Pregnancy

et al. 2003

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“…Emzirme döneminde kullanılan kemoterapötikler yenidoğandaki düşük karaciğer ve böbrek klirensi sebebiyle yeni doğanda toksisiteye sebep olabilir. Bu yüzden kemoterapi alan hastalara emzirme yasaklanmalıdır 14 .…”

Section: Kemoterapiunclassified

Gebelikte Jinekolojik Kanserler

İlhan¹,

Yılmaz²,

Kebapçılar³

2015

Arşiv Kaynak Tarama Dergisi

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The number of cancer diagnosis during pregnancy is increasing as a result of becoming widespread of screening tests and advanced pregnancy age. Gynecologic oncologists and oncologist make effort for medical and surgical treatments of cancer without any side effect on fetal well-being. In this review, the diagnosis, treatments and fetal effects of gynecologic cancers during pregnancy was discussed.

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“…Unlike nongravid patients, the majority of ovarian malignancies diagnosed during pregnancy are confined to the ovary. 35,39,[44][45][46] In a study of 202 cases of ovarian cancers in pregnancy, 91% had stage I tumors. 39 In addition, ovarian cancers in pregnancy are more likely to be low grade.…”

Section: Expectant Managementmentioning

confidence: 99%

“…39 In addition, ovarian cancers in pregnancy are more likely to be low grade. 39,45,46 The overall mortality due to ovarian cancer in pregnancy is 4.7%. 39 This comparatively low mortality rate is likely due to the early stage of disease, the high prevalence of low malignant potential tumors and germ cell tumors both of which have an excellent prognosis, and the young age of the patients rather than some protective effect of the pregnancy itself.…”

Section: Expectant Managementmentioning

confidence: 99%

Adnexal Masses in Pregnancy: Diagnosis and Management

Graham¹

2007

Donald School Journal of Ultrasound in Obstetrics and Gynecology

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Abstract:The widespread use of ultrasound in obstetrics has led to an increase in the diagnosis of asymptomatic adnexal masses in pregnancy. Ultrasound is an accurate and safe method for diagnosing the etiology of an adnexal mass and distinguishing benign from malignant pathology. The management of an adnexal mass in pregnancy is controversial. Historically, it was recommended that any adnexal mass be removed electively in the second trimester to exclude malignancy and prevent complications such as torsion, rupture, and obstruction of labor. More recent recommendations have limited surgical intervention in pregnancy to symptomatic adnexal masses and those that are highly suggestive of malignancy. Surgery in pregnancy is associated with an increased risk of adverse pregnancy outcomes. However, laparoscopy appears to be a safe alternative to laparotomy for benign masses when performed by experienced surgeons. Key words: Adnexal mass, pregnancy complications, ultrasound Learning objectives• To list the differential diagnoses of adnexal masses in pregnancy • To interpret ultrasound images of adnexal masses and distinguish benign from malignant masses • To describe the management options for adnexal masses in pregnancy, including the indications and options for surgical intervention.

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Ovarian Cancer Complicating Pregnancy

Cited by 125 publications

References 39 publications

Adnexal Masses in Pregnancy

Adnexal Masses in Pregnancy

Gebelikte Jinekolojik Kanserler

Adnexal Masses in Pregnancy: Diagnosis and Management

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