Ovarian Adenocarcinoma with Serous Effusions Appeared after a Mammary Adenocarcinoma: A Case Report

Abstract

The ovarian adenocarcinoma is an aggressive cancer which has the highest mortality rate of all the gynecological cancers. More than 1/3 of the patients requests medical attention for ascites and pleural effusions. The association of the triad ovarian tumor, ascites and pleural effusions raises diagnostic issues and may lead to delay of adequate treatment. We present the case of a 56 years old female patient, initially diagnosed with bilateral mammary adenocarcinoma, who was treated with chemo-and radiotherapy. Subsequently she developed another adenocarcinoma -this time with ovarian localization. The particularity of this case consists of the risk factors that contributed to the appearance of the ovarian adenocarcinoma with serous effusions, represented by the family and personal history of the patient.

Successful Implementation of HITOC and HIPEC in the Management of Advanced Ovarian Carcinoma with Pleural and Peritoneal Carcinomatosis

“…The absence of complications contributed to the overall positive trajectory of the patient’s recovery, allowing the second surgical intervention to be performed, which consisted of peritoneal CRS and HIPEC one month later. It consisted of an en bloc posterior pelvic exenteration with a pelvic peritonectomy [ 1 , 2 , 3 , 4 , 5 , 6 , 7 , 8 , 9 , 10 ], lymphadenectomy, and en bloc enlarged enterectomy with a total colectomy and terminal ileostomy ( Figure 7 and Figure 8 ). It is worth noting that lymphadenectomy plays a crucial role in peritoneal carcinomatosis cases by providing essential insights into regional lymph node involvement in advanced disease forms, aiding in accurate staging, guiding therapeutic decisions, and enhancing prognostic assessments.…”

“…It is worth noting that lymphadenectomy plays a crucial role in peritoneal carcinomatosis cases by providing essential insights into regional lymph node involvement in advanced disease forms, aiding in accurate staging, guiding therapeutic decisions, and enhancing prognostic assessments. The HIPEC lavage was performed using cisplatin 100 mg/m 2 and doxorubicin 50 mg/m 2 at 42 degrees Celsius for 90 min [ 6 , 7 , 8 , 9 , 10 , 11 ]. The patient’s postoperative evolution after HIPEC was marked by a combination of physiological stability, effective pain management, restored organ functions, and an overall improvement in wellbeing.…”